微波辐照三组分Biginelli反应高效合成新型N,N ' -二苯甲酰-嘧啶-2(1H)- ones

V. Deepthi, S. Triloknadh, B. Nagaraju, C. Rao
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引用次数: 1

摘要

采用环境友好的微波诱导有机合成方法,进行三组分Biginelli反应合成N,N-二苯甲酰基嘧啶- 21衍生物。该方案的优点包括提高收率,缩短反应时间,操作简单,避免有机溶剂和环保制备,指导绿色合成的新趋势。
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An Efficient Synthesis of Novel N,N`-Dibenzoyl- pyrimidin-2(1H)-Ones Using Microwave Irradiation via Three-Component Biginelli Reaction
Environmentally benign microwave induced method of organic synthesis has been taken up to carry out three component Biginelli reaction for the synthesis of N,N-dibenzoyl pyrimidin-2one derivatives. The advantages of this protocol include enhanced yield, reduced reaction time, operational simplicity, avoidance of organic solvents and eco-friendly preparation that directs towards new trends in green synthesis.
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