埃塞俄比亚东昭和Adama医院医学院结核病复诊率及治疗效果评估

J. Lenjisa, Birhanu Tolosa, M. Woldu, Dumessa Edessa Negassa, Getu Bayisa Wakjira
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引用次数: 8

摘要

背景:尽管以前接受过治疗的结核病患者(再治疗病例)的比例正以惊人的速度增长,但缺乏有关其规模和治疗结果的数据。因此,本研究旨在评估埃塞俄比亚Adama医院医学院(AHMC)的结核病再治疗病例率及其治疗效果。方法:采用回顾性横断面调查方法,对2014年4 - 5月732例登记结核病患者的资料进行回顾性分析。数据分析采用SPSS 20.0版本。结果:732例TB患者中,有147例(20%)登记为再治疗病例。其中,16例(11%)复发,13例(9%)复发,23例(16%)失败,95例(64%)被归类为“其他”,其中61例(64.9%)患有痰涂片阴性肺结核(PTB), 34例(35.1%)患有额外的PTB (EPTB)。再治疗病例更可能发生在HIV阳性的48例(59%)个体中。治疗结果方面,治疗成功率(治愈+完成治疗)65例(63.7%)。13例(12.8%)登记为死亡,10例(9.8%)登记为失败,9例(8.8%)登记为违约,5例(4.9%)登记为转出病例到其他卫生机构。艾滋病毒阳性个体的治疗效果较差的可能性更大(54%)。结论:与同类研究相比,本研究获得的结核病再治疗病例患病率较高。同样,他们的治疗成功率(TSR)比全国数字低。因此,应更加重视结核病再治疗病例的预防和治疗,以避免埃塞俄比亚结核病的社会和经济负担。
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Assessment of Tuberculosis Retreatment Case Rate and Its Treatment Outcomesat Adama Hospital Medical College, East Showa, Ethiopia
Background: Even though the proportion of previously treated TB patients’ (retreatment cases) is increasing at alarming rate, there is scarcity of data regarding their magnitude and treatment outcomes. Therefore, this study is meant to assess TB retreatment case rate and their treatment outcomes at Adama hospital medical college (AHMC) in Ethiopia. Methods: The study employed a retrospective cross-sectional survey where a total of 732 registered TB patients’ data were reviewed between Aprils to May 2014. Data analysis was done using SPSS version 20.0. Results: In this study, 147 (20%) of 732 TB cases were registered as retreatment cases. Of these, 16 (11%) relapse, 13 (9%) return after defaulted (RAD), 23 (16%) failure and 95 (64%) were categorized as ‘other’ among which 61 (64.9%) had sputum smear-negative pulmonary TB (PTB) and 34 (35.1%) had extra PTB (EPTB). Retreatment case is more likely to occur in HIV positive 48 (59%) individuals. Regarding their treatment outcomes, treatment success rate (cure plus treatment completed) of 65 (63.7%) was obtained. Whereas 13 (12.8%) registered as died, 10 (9.8%) as failure, 9 (8.8%) as defaulters and 5 (4.9%) as transferred out cases to other health facility. HIV positive individuals are more likely (54%) to have poor treatment outcomes. Conclusion: The prevalence of TB retreatment cases obtained in this study was higher as compared to similar studies. Similarly, their treatment success rate (TSR) was lower as compared to the national figure. Therefore, more attention should be given to the prevention and treatment of TB retreatment cases to avoid social and economic burden of tuberculosis in Ethiopia.
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