NGHA患者PRRT治疗期间的辐射防护

N. Senhou
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引用次数: 0

摘要

医学辐射防护原则上包括医疗照射、职业照射和与各种临床情况有关的公众照射。医疗暴露不仅涉及患者,还涉及其家属和医务人员。肽受体放射性核素治疗(PRRT)是一种用于治疗神经内分泌肿瘤(NET)的分子靶向治疗。在沙特阿拉伯的国民警卫队医院PRRT疗法是一种新的治疗方法由于缺乏参考资料或讲座,这种治疗的辐射防护是未知的,在某些情况下,它可能被认为是一种低污染的治疗方法,因为它是一种放射物,PRRT向体内的肿瘤提供高剂量的辐射来破坏或减缓它们的生长,减少疾病的副作用,放射物的治疗方法正在增加。本专题的目的是报告PRRT的现状,澄清与PRRT相关的辐射防护问题,并展望未来。医务人员往往没有意识到接触贝塔辐射的高风险,现有或使用的不适当剂量计会使情况更加复杂,使用的个人剂量计往往没有正确佩戴。在贴标签(制备)和输液(给药)过程中,工作人员的皮肤剂量应谨慎进行,因为如果不严格遵守安全标准,技术人员在制备过程中的肢体暴露可能超过剂量限制。PRRT需要制定辐射防护标准,因为它使用未密封的放射性核素,并对人类提供治疗性辐射剂量。本专题的目的是提出在准备和管理期间个人做法的大变化,并暗示改善辐射安全的选择
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Radiation protection during PRRT therapy in NGHA
Radiation protection in medicine covers in principle, medical exposure, occupational exposure, and public exposure in association with various clinical circumstances. Medical exposure involves not only patients but also their relatives and medical staff. Peptide receptor radionuclide therapy (PRRT) is a molecular targeted therapy used to treat neuroendocrine tumors (NET). In National Guard Hospital in Saudi Arabia the PRRT therapy is kind of new treatment and the radioprotection for such treatment was unknown because of the lack of reference or lectures, in some cases it may be considered as a low contamination treatment because it’s a beta emission, PRRT delivers high doses of radiation to tumors in the body to destroy or slow their growth and reduce disease side effects, Therapeutic procedures with beta emitters are growing. The purpose of this topic is to report on the current state of PRRT, to clarify the issues of radiation protection associated with PRRT, and to show future prospects. Medical staff is often not aware of the high risk of exposure to beta radiation, inappropriate dose meters available or used can make it more complicated, the personal dose meters used often are not worn properly. Skin dose of staff during labelling(preparation) and infusion (administration) should be done carefully because extremity exposure of technicians during preparation may exceed dose limit if safety standards are not strictly kept. PRRT requires deliberate radiation protection standards as it uses unsealed radionuclides and gives therapeutic radiation doses in humans. the goal of this topic is the proposal of large variations of individual practices during preparation and administration and to imply options for improving radiation safety
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