超重和非肥胖吸烟者胰岛素水平的比较

E. Karakoc, B. Yalcin, Esra Yalcin
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引用次数: 1

摘要

心血管疾病是世界上最常见的发病和死亡原因。吸烟和肥胖是导致这些疾病的最重要的可避免原因。然而,在土耳其,关于肥胖(中枢性和雄激素性)对吸烟者胰岛素水平的影响的研究还不够。有了这个目的;对1997年11月至1998年5月期间在塔克西姆医院第二内科诊所接受治疗的211名志愿者、吸烟者和18岁以上患者中符合研究标准的84名患者进行了口服葡萄糖耐量试验(OGTT)。同时检测患者的总胆固醇、HDL、LDL、甘油三酯水平。测量患者身高、体重、腰围。根据这些数据,计算体重指数(BMI)和腰围(WC)。采用Fagerstrom尼古丁依赖试验(FNDT)评估患者的尼古丁成瘾程度,并计算每包/年的量。根据研究数据,超重患者与正常体重患者在年龄、FNDT评分、胰岛素、TC、LDL和HDL水平上均无差异(p>0.05)。另一方面;两组患者BMI值、WC值(不同性别)、TG水平差异均有统计学意义。在回归分析中;BMI [OR: 1.512, (95% CI min=0.928, max=2.069)]和WC [OR: 1.912, (95% CI min=1.051, max=2.125)]是胰岛素增加的危险因素。关于大规模参与横断面研究的主题的附加信息。改变生活方式(戒烟和有效控制体重)的更多行动可能会增加人群中心血管疾病的风险。
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The comparison of insulin levels between over weighted and non-obese smokers
Cardiovasculer diseases are the most common reason for morbidity and mortality in the world. Smoking and obesity are among the most important avoidable reasons for these diseases. However, in Turkey, there are not enough studies about the effect of obesity (central and androgenic) on insulin levels of smokers. With this aim; oral glucose tolerance test (OGTT) was performed on 84 patients who meet the study criteria among 211 patients treated at the second internal diseases clinic of Taksim Hospital between November 1997 and May 1998, who were volunteers, smokers and older than 18. In addition, the total cholesterol, HDL, LDL and triglicerid levels of these patiens were checked. Heights, weights and waist circumferences of patients were measured. From these datas, body mass indexes (BMI) and waist circumferences (WC) were calculated. Nicotine addiction levels of patients were evaluated by Fagerstrom Nicotine Dependency Test (FNDT) and package/year amounts were calculated. According to the results based on the data obtained from the studies, no difference were determined (p>0.05), in ages, FNDT scores, insulin, TC, LDL and HDL levels between overweighted and normal weighted patients. On the other hand; there was statistically significant difference between two groups in BMI values, WC measurements (between different genders) and TG levels. In the regression analysis; BMI [OR: 1.512, (95% CI min=0.928, max=2.069)] and WC [OR: 1.912, (95% CI min=1.051, max=2.125)] was founded as a risk factor for the insulin increment. Additional information about the subject for the large participation cross-sectional studies. More action about life style modification (smoking cessation and an effective weight control) may increase risk of cardiovascular diseases in populations.
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