蛋白质结构分析的PROLOG方法

Geoffrey J. Barton , Christopher J. Rawlings
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引用次数: 6

摘要

本文详细介绍了一个用逻辑编程语言PROLOG实现的蛋白质结构数据库。该数据库允许灵活地访问蛋白质结构层次的原子、残基、二级结构和拓扑级别的结构信息。在PROLOG中实现了用于二级结构定义的kbusch和Sander算法的扩展版本,形成了数据库的一个组成部分。对于蛋白质结构分析,PROLOG系统在灵活性上比传统的编程语言(如Fortran)和使用SQL的关系数据库管理系统(Relational Database Management Systems)有显著的优势。
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A PROLOG approach to analysing protein structure

This paper provides a detailed description of a database of protein structure implemented in the logic programming language PROLOG. The database allows flexible access to structural information at the atom, residue, secondary structure and topology levels of the protein structural hierarchy. An extended version of the Kabsch and Sander algorithm for secondary structure definition has been implemented in PROLOG, forming an integral part of the database. For protein structure analysis, the PROLOG system shows significant advantages in flexibility over conventional programming languages such as Fortran, and Relational Database Management Systems using SQL.

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