{"title":"异烟酸催化丙二腈、各种醛和巴比妥酸衍生物的串联knoevenagel - michael -环缩合反应","authors":"A. Moosavi‐Zare, H. Goudarziafshar, Z. Jalilian","doi":"10.33945/sami/pcbr.2019.2.2.3","DOIUrl":null,"url":null,"abstract":"In this work, we have reported the preparation of pyrano[2,3-d]pyrimidine dione derivatives by the tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives at the presence of isonicotinic acid as an efficient organocatalyst.","PeriodicalId":20668,"journal":{"name":"Progress in Chemical and Biochemical Research","volume":"10 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"14","resultStr":"{\"title\":\"Tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives using isonicotinic acid as an efficient catalyst\",\"authors\":\"A. Moosavi‐Zare, H. Goudarziafshar, Z. Jalilian\",\"doi\":\"10.33945/sami/pcbr.2019.2.2.3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this work, we have reported the preparation of pyrano[2,3-d]pyrimidine dione derivatives by the tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives at the presence of isonicotinic acid as an efficient organocatalyst.\",\"PeriodicalId\":20668,\"journal\":{\"name\":\"Progress in Chemical and Biochemical Research\",\"volume\":\"10 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"14\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Progress in Chemical and Biochemical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33945/sami/pcbr.2019.2.2.3\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in Chemical and Biochemical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33945/sami/pcbr.2019.2.2.3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 14
摘要
在这项工作中,我们报道了在异烟酸作为有效的有机催化剂存在下,丙二腈、各种醛和巴比妥酸衍生物通过串联knoevenagel - michael -环缩合反应制备吡喃[2,3-d]嘧啶二酮衍生物。
Tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives using isonicotinic acid as an efficient catalyst
In this work, we have reported the preparation of pyrano[2,3-d]pyrimidine dione derivatives by the tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives at the presence of isonicotinic acid as an efficient organocatalyst.