Krishnan Baburaj , David M Reid MD FRCPEdin FRCPLon
{"title":"骨科:软组织、代谢及恶性肌软化","authors":"Krishnan Baburaj , David M Reid MD FRCPEdin FRCPLon","doi":"10.1383/wohm.2006.3.4.179","DOIUrl":null,"url":null,"abstract":"<div><p>Osteomalacia is characterized by defective mineralization of bone, leading to an accumulation of unmineralized bone matrix (osteoid). Rickets represents the occurrence of this defect in growing children before the closure of epiphysis. In osteomalacia, there is a reduction in the mineralized bone:matrix ratio, unlike osteoporosis, where this ratio remains normal. There is sufficient bone volume, but the bone has reduced calcification. This contribution discusses the: aetiology, clinical features, investigations and management of osteomalacia.</p></div>","PeriodicalId":101284,"journal":{"name":"Women's Health Medicine","volume":"3 4","pages":"Pages 179-180"},"PeriodicalIF":0.0000,"publicationDate":"2006-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1383/wohm.2006.3.4.179","citationCount":"0","resultStr":"{\"title\":\"Osteomalacia\",\"authors\":\"Krishnan Baburaj , David M Reid MD FRCPEdin FRCPLon\",\"doi\":\"10.1383/wohm.2006.3.4.179\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Osteomalacia is characterized by defective mineralization of bone, leading to an accumulation of unmineralized bone matrix (osteoid). Rickets represents the occurrence of this defect in growing children before the closure of epiphysis. In osteomalacia, there is a reduction in the mineralized bone:matrix ratio, unlike osteoporosis, where this ratio remains normal. There is sufficient bone volume, but the bone has reduced calcification. This contribution discusses the: aetiology, clinical features, investigations and management of osteomalacia.</p></div>\",\"PeriodicalId\":101284,\"journal\":{\"name\":\"Women's Health Medicine\",\"volume\":\"3 4\",\"pages\":\"Pages 179-180\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1383/wohm.2006.3.4.179\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Women's Health Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1744187006701986\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Women's Health Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1744187006701986","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Osteomalacia is characterized by defective mineralization of bone, leading to an accumulation of unmineralized bone matrix (osteoid). Rickets represents the occurrence of this defect in growing children before the closure of epiphysis. In osteomalacia, there is a reduction in the mineralized bone:matrix ratio, unlike osteoporosis, where this ratio remains normal. There is sufficient bone volume, but the bone has reduced calcification. This contribution discusses the: aetiology, clinical features, investigations and management of osteomalacia.
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