处方模式在2型糖尿病门诊患者在斋浦尔三级保健中心,印度

Q4 Medicine Scripta Medica Pub Date : 2022-01-01 DOI:10.5937/scriptamed53-35899
Jaya Dadhich, Devendra Dadhich, R. Dadheech, N. Gupta, R. Chandel, Shivankan Kakkar
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摘要

背景:在过去的几年中,印度的糖尿病患病率出现了意想不到的增长。本研究计划分析抗高血糖药物的处方模式,并评估印度拉贾斯坦邦首席部长免费药物计划的影响。其目的是评估、监测并在可能的情况下提出修改处方做法的建议,以使医疗保健合理化,并协助尽量减少药物不良反应。方法:这是一项为期12个月的横断面观察性研究。选取印度拉贾斯坦邦斋浦尔市西姆斯医学院医院(一家三级保健医院,位于斋浦尔)室外内分泌科的400例已知2型糖尿病(T2DM)患者,采用世界卫生组织(WHO)处方指标对其处方进行分析。结果:年龄40 ~ 50岁,平均(53.76±8.84)岁,以男性为主(57.5%)。其中67.5%的患者肥胖(平均BMI为29.79±3.26)。所有的抗高血糖药物都只用通用名来开处方。二甲双胍是最常用的抗高血糖药物。在固定剂量联合用药中,格列美脲与二甲双胍最常见(40.75%),抗高血糖药物加药最多的是替尼格列汀(51.5%),其次是吡格列酮(30.5%)。53.25%的患者同时使用胰岛素和口服抗高血糖药物。结论:斋浦尔三级医院内分泌科门诊患者抗高血糖药物处方情况良好。
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Prescribing patterns in type 2 diabetes mellitus outpatients at a tertiary care centre in Jaipur, India
Background: Over the last few years, an unexpected increase in the prevalence of diabetes in India have been witnessed. The present study was planned to analyse prescribing patterns of anti-hyperglycaemic drugs and assess the influence of Chief Minister's Free Drug Scheme in Rajasthan, India. It aimed to evaluate, monitor and if possible, suggest modifications in prescribing practices to make medical care rational and also to assist minimising adverse drug reactions (ADRs). Methods: This was a cross-sectional, observational study carried out for a 12-month period. A total 400 known patients of type 2 diabetes mellitus (T2DM) from endocrinology outdoor of SMS Medical College Hospital (a tertiary care hospital in Jaipur, Rajasthan, India) were recruited and their prescriptions were analysed using the World Health Organization (WHO) prescribing indicators. Results: Most commonly observed age group was of 40-50 years (mean age 53.76 ± 8.84), with a male preponderance (57.5 %). Among them, 67.5 % of patients were found to be obese (mean BMI 29.79 ± 3.26). All anti-hyperglycaemic were prescribed in their generic names only. Metformin was the most frequently prescribed anti-hyperglycaemic agent. Among the fixed dose combinations, the most common was that of glimepiride and metformin (40.75 %), while most prescribed add on anti-hyperglycaemic was teneligliptin (51.5 %), followed by pioglitazone (30.5 %). A total of 53.25 % of these patients received insulin along with oral anti-hyperglycaemic agents. Conclusion: The anti-hyperglycaemic agent prescribing among endocrinology outpatients at tertiary care hospital in Jaipur was found to be satisfactory.
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13
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