{"title":"评价急诊高血压危重患者使用艾司洛尔的有效性和安全性","authors":"N. I. Gaponova","doi":"10.24884/2072-6716-2023-24-2-33-39","DOIUrl":null,"url":null,"abstract":" In 94 patients, suffering from complicated or uncomplicated hypertensic crisis, the efficiency and safety of esmolol administration in pre-hospital stage of emergency medical care was examined. Unique pharmacokinetics of esmolol allow us to achieve significant arterial tension decrease during the first minutes of the intravenous injection, meanwhile antihypertensive effect increases till 20 minutes and elimination half-life is 9 minutes. Esmolol dosage was selected depending on initial hemodynamic indicators and hypertensic crisis complications. In order to evaluate efficiency and safety in this research the following indicators were measured: sistolic blood pressure, diastolic blood pressure, heart rate, electrocardiogram and SpO2 , respiratory function monitoring.","PeriodicalId":37398,"journal":{"name":"Sklifosovsky Journal Emergency Medical Care","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of the efficiency and safety of Esmolol in patients, who suffers from hypertensic crisis, within the conditions of emergency medical care\",\"authors\":\"N. I. Gaponova\",\"doi\":\"10.24884/2072-6716-2023-24-2-33-39\",\"DOIUrl\":null,\"url\":null,\"abstract\":\" In 94 patients, suffering from complicated or uncomplicated hypertensic crisis, the efficiency and safety of esmolol administration in pre-hospital stage of emergency medical care was examined. Unique pharmacokinetics of esmolol allow us to achieve significant arterial tension decrease during the first minutes of the intravenous injection, meanwhile antihypertensive effect increases till 20 minutes and elimination half-life is 9 minutes. Esmolol dosage was selected depending on initial hemodynamic indicators and hypertensic crisis complications. In order to evaluate efficiency and safety in this research the following indicators were measured: sistolic blood pressure, diastolic blood pressure, heart rate, electrocardiogram and SpO2 , respiratory function monitoring.\",\"PeriodicalId\":37398,\"journal\":{\"name\":\"Sklifosovsky Journal Emergency Medical Care\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sklifosovsky Journal Emergency Medical Care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24884/2072-6716-2023-24-2-33-39\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sklifosovsky Journal Emergency Medical Care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24884/2072-6716-2023-24-2-33-39","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Evaluation of the efficiency and safety of Esmolol in patients, who suffers from hypertensic crisis, within the conditions of emergency medical care
In 94 patients, suffering from complicated or uncomplicated hypertensic crisis, the efficiency and safety of esmolol administration in pre-hospital stage of emergency medical care was examined. Unique pharmacokinetics of esmolol allow us to achieve significant arterial tension decrease during the first minutes of the intravenous injection, meanwhile antihypertensive effect increases till 20 minutes and elimination half-life is 9 minutes. Esmolol dosage was selected depending on initial hemodynamic indicators and hypertensic crisis complications. In order to evaluate efficiency and safety in this research the following indicators were measured: sistolic blood pressure, diastolic blood pressure, heart rate, electrocardiogram and SpO2 , respiratory function monitoring.
期刊介绍：
The Journal "Neotlozhnaia meditsinskaia pomoshch" (parallel titles: Zhurnal im. N.V. Sklifosovskogo "Neotlozhnai︠a︡ medit︠s︡inskai︠a︡ pomoshch", "Sklifosovsky Journal of Emergency Medical Care") seeks to publish original research articles, literature reviews, case reports, brief reports on clinical practice, and other suitable material submitted by professionals involved in the diagnosis and treatment of acute medical and surgical conditions.
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