基于非负矩阵分解的统一多视图聚类方法用于癌症亚型分型

IF 0.5 4区 计算机科学 Q4 COMPUTER SCIENCE, SOFTWARE ENGINEERING International Journal of Data Warehousing and Mining Pub Date : 2023-03-17 DOI:10.4018/ijdwm.319956
Zhanpeng Huang, Jiekang Wu, Jinlin Wang, Yu Lin, Xiaohua Chen
{"title":"基于非负矩阵分解的统一多视图聚类方法用于癌症亚型分型","authors":"Zhanpeng Huang, Jiekang Wu, Jinlin Wang, Yu Lin, Xiaohua Chen","doi":"10.4018/ijdwm.319956","DOIUrl":null,"url":null,"abstract":"Non-negative matrix factorization (NMF) has gained sustaining attention due to its compact leaning ability. Cancer subtyping is important for cancer prognosis analysis and clinical precision treatment. Integrating multi-omics data for cancer subtyping is beneficial to uncover the characteristics of cancer at the system-level. A unified multi-view clustering method was developed via adaptive graph and sparsity regularized non-negative matrix factorization (multi-GSNMF) for cancer subtyping. The local geometrical structures of each omics data were incorporated into the procedures of common consensus matrix learning, and the sparsity constraints were used to reduce the effect of noise and outliers in bioinformatics datasets. The performances of multi-GSNMF were evaluated on ten cancer datasets. Compared with 10 state-of-the-art multi-view clustering algorithms, multi-GSNMF performed better by providing significantly different survival in 7 out of 10 cancer datasets, the highest among all the compared methods.","PeriodicalId":54963,"journal":{"name":"International Journal of Data Warehousing and Mining","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A Unified Multi-View Clustering Method Based on Non-Negative Matrix Factorization for Cancer Subtyping\",\"authors\":\"Zhanpeng Huang, Jiekang Wu, Jinlin Wang, Yu Lin, Xiaohua Chen\",\"doi\":\"10.4018/ijdwm.319956\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Non-negative matrix factorization (NMF) has gained sustaining attention due to its compact leaning ability. Cancer subtyping is important for cancer prognosis analysis and clinical precision treatment. Integrating multi-omics data for cancer subtyping is beneficial to uncover the characteristics of cancer at the system-level. A unified multi-view clustering method was developed via adaptive graph and sparsity regularized non-negative matrix factorization (multi-GSNMF) for cancer subtyping. The local geometrical structures of each omics data were incorporated into the procedures of common consensus matrix learning, and the sparsity constraints were used to reduce the effect of noise and outliers in bioinformatics datasets. The performances of multi-GSNMF were evaluated on ten cancer datasets. Compared with 10 state-of-the-art multi-view clustering algorithms, multi-GSNMF performed better by providing significantly different survival in 7 out of 10 cancer datasets, the highest among all the compared methods.\",\"PeriodicalId\":54963,\"journal\":{\"name\":\"International Journal of Data Warehousing and Mining\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2023-03-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Data Warehousing and Mining\",\"FirstCategoryId\":\"94\",\"ListUrlMain\":\"https://doi.org/10.4018/ijdwm.319956\",\"RegionNum\":4,\"RegionCategory\":\"计算机科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"COMPUTER SCIENCE, SOFTWARE ENGINEERING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Data Warehousing and Mining","FirstCategoryId":"94","ListUrlMain":"https://doi.org/10.4018/ijdwm.319956","RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"COMPUTER SCIENCE, SOFTWARE ENGINEERING","Score":null,"Total":0}
引用次数: 1

摘要

非负矩阵分解(NMF)以其紧凑的学习能力一直受到人们的关注。肿瘤分型对肿瘤预后分析和临床精准治疗具有重要意义。整合癌症亚型的多组学数据有助于在系统水平上揭示癌症的特征。提出了一种基于自适应图和稀疏正则化非负矩阵分解(multi-GSNMF)的统一多视图聚类方法。将每个组学数据的局部几何结构纳入共识矩阵学习过程,并使用稀疏性约束来降低生物信息学数据集中的噪声和异常值的影响。在10个癌症数据集上对多重gsnmf的性能进行了评价。与10种最先进的多视图聚类算法相比,multi-GSNMF表现更好,在10个癌症数据集中有7个提供了显著不同的生存率,在所有比较方法中最高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
A Unified Multi-View Clustering Method Based on Non-Negative Matrix Factorization for Cancer Subtyping
Non-negative matrix factorization (NMF) has gained sustaining attention due to its compact leaning ability. Cancer subtyping is important for cancer prognosis analysis and clinical precision treatment. Integrating multi-omics data for cancer subtyping is beneficial to uncover the characteristics of cancer at the system-level. A unified multi-view clustering method was developed via adaptive graph and sparsity regularized non-negative matrix factorization (multi-GSNMF) for cancer subtyping. The local geometrical structures of each omics data were incorporated into the procedures of common consensus matrix learning, and the sparsity constraints were used to reduce the effect of noise and outliers in bioinformatics datasets. The performances of multi-GSNMF were evaluated on ten cancer datasets. Compared with 10 state-of-the-art multi-view clustering algorithms, multi-GSNMF performed better by providing significantly different survival in 7 out of 10 cancer datasets, the highest among all the compared methods.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
International Journal of Data Warehousing and Mining
International Journal of Data Warehousing and Mining COMPUTER SCIENCE, SOFTWARE ENGINEERING-
CiteScore
2.40
自引率
0.00%
发文量
20
审稿时长
>12 weeks
期刊介绍: The International Journal of Data Warehousing and Mining (IJDWM) disseminates the latest international research findings in the areas of data management and analyzation. IJDWM provides a forum for state-of-the-art developments and research, as well as current innovative activities focusing on the integration between the fields of data warehousing and data mining. Emphasizing applicability to real world problems, this journal meets the needs of both academic researchers and practicing IT professionals.The journal is devoted to the publications of high quality papers on theoretical developments and practical applications in data warehousing and data mining. Original research papers, state-of-the-art reviews, and technical notes are invited for publications. The journal accepts paper submission of any work relevant to data warehousing and data mining. Special attention will be given to papers focusing on mining of data from data warehouses; integration of databases, data warehousing, and data mining; and holistic approaches to mining and archiving
期刊最新文献
Fishing Vessel Type Recognition Based on Semantic Feature Vector Optimizing Cadet Squad Organizational Satisfaction by Integrating Leadership Factor Data Mining and Integer Programming Hybrid Inductive Graph Method for Matrix Completion A Fuzzy Portfolio Model With Cardinality Constraints Based on Differential Evolution Algorithms Dynamic Research on Youth Thought, Behavior, and Growth Law Based on Deep Learning Algorithm
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1