纳米技术在草药中的应用综述

Krishnasis Chakraborty, A. Shivakumar, Sundaram Ramachandran
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引用次数: 30

摘要

草药在世界各地已经使用多年;特别是在印度,草药的需求量很大。草药的使用越来越多,因为它们能够治疗不同的疾病,而且副作用更小。新型给药系统(NDDS)的发展对于克服生物利用度差、体内稳定性、水不溶性、肠道吸收和作用部位不特异性等诸多限制具有重要意义。纳米科学作为NDDS与传统医学体系的整合,丰富了草药治疗癌症等慢性疾病和破坏性疾病的潜力。根据纳米颗粒的性质,可以采用聚合物纳米颗粒、磁性纳米颗粒和金属纳米颗粒等新方法来合成纳米颗粒。这些先进的技术将为表征纳米粒子的物理和化学性质以及确定其毒性特征提供线索。本文将简要介绍纳米粒子的合成、各种生产技术的表征以及纳米技术对智能草药的未来影响。
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Nano-technology in herbal medicines: A review
Herbal medicines have been used from years throughout the world; especially in India, herbal medicines are in high demand. The use of herbal medicines has increased because of their ability to treat different diseases with fewer side effects. The development of novel drug delivery system (NDDS) is of considerable importance to overcome various constraints like poor bioavailability, in vivo stability, aqueous insolubility, intestinal absorption and unspecific site of action. The integration of the Nano science as a NDDS in traditional system of medicine enriches the potential of herbal drugs for treating chronic diseases such as cancer and ravaging diseases. The synthesis of nanoparticles can be achieved by adopting the novel methodologies such as Polymer nanoparticle, Magnetic nanoparticle and Metallic nanoparticle depending on characteristic of the nanoparticles. The advanced technologies will shed lights for characterizing the nanoparticles to determine the toxicity profiles for their physical and chemical properties. This review article will provide a brief discussion of Nanoparticles synthesis, characterization by various techniques for production and its future impact of nanotechnology on smart herbal drugs.
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