停止质子泵抑制剂后胃食管反流症状的加重与食管酸暴露增加无关

Neurogastroenterology & Motility Pub Date : 2020-01-01 DOI:10.1111/nmo.13735

Yoshimasa Hoshikawa, K. Nikaki, S. Sonmez, K. Nakagawa, E. Yazaki, D. Sifrim, P. Woodland

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引用次数: 3

摘要

有反流症状的患者停用长期质子泵抑制剂(PPIs)可能具有挑战性，因为停药后症状往往会加剧。其机制尚不清楚。我们的目的是评估停止长期PPIs对胃灼热患者的影响及其与食管酸暴露的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Exacerbation of gastroesophageal reflux symptoms after discontinuation of proton pump inhibitors is not associated with increased esophageal acid exposure

Discontinuation of long‐term proton pump inhibitors (PPIs) on patients with reflux symptoms can be challenging, as symptoms often exacerbate after stopping. The mechanism remains unknown. Our aim was to evaluate the impact of stopping long‐term PPIs on patients with heartburn, and its association with esophageal acid exposure.

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Neurogastroenterology & Motility

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