{"title":"年龄相关性黄斑变性患者血清硫化氢升高","authors":"Bharathidevi Sr","doi":"10.23880/oajo-16000281","DOIUrl":null,"url":null,"abstract":"Introduction: Age related macular degeneration is one of the major causes of global blindness and vision impairment. The study was done to determine the levels of hydrogen sulfide (H2S) in AMD subjects in the study cohort. Methods: Twenty-six blood samples were collected, 12 control and 14 AMD subjects, the serum obtained from these samples were used for the measurement of H2S by Methylene blue (MB) assay and IL6 using ELISA. Results: We observed that both the levels of H2S and IL6 to be elevated in AMD subjects when compared to control and H2S and IL6 showed a positive correlation. Conclusion: We propose H2S to be a marker in both dry and wet AMD","PeriodicalId":91939,"journal":{"name":"Open access journal of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Elevated Serum Hydrogen Sulfide in Age Related Macular Degeneration\",\"authors\":\"Bharathidevi Sr\",\"doi\":\"10.23880/oajo-16000281\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Age related macular degeneration is one of the major causes of global blindness and vision impairment. The study was done to determine the levels of hydrogen sulfide (H2S) in AMD subjects in the study cohort. Methods: Twenty-six blood samples were collected, 12 control and 14 AMD subjects, the serum obtained from these samples were used for the measurement of H2S by Methylene blue (MB) assay and IL6 using ELISA. Results: We observed that both the levels of H2S and IL6 to be elevated in AMD subjects when compared to control and H2S and IL6 showed a positive correlation. Conclusion: We propose H2S to be a marker in both dry and wet AMD\",\"PeriodicalId\":91939,\"journal\":{\"name\":\"Open access journal of ophthalmology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open access journal of ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23880/oajo-16000281\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open access journal of ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23880/oajo-16000281","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Elevated Serum Hydrogen Sulfide in Age Related Macular Degeneration
Introduction: Age related macular degeneration is one of the major causes of global blindness and vision impairment. The study was done to determine the levels of hydrogen sulfide (H2S) in AMD subjects in the study cohort. Methods: Twenty-six blood samples were collected, 12 control and 14 AMD subjects, the serum obtained from these samples were used for the measurement of H2S by Methylene blue (MB) assay and IL6 using ELISA. Results: We observed that both the levels of H2S and IL6 to be elevated in AMD subjects when compared to control and H2S and IL6 showed a positive correlation. Conclusion: We propose H2S to be a marker in both dry and wet AMD
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