心脏手术后患者生命周期分析

V. Hajiyev, T. Erkenov, A. Smechowski, S. Just, O. Grimmig, D. Fritzsche
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摘要

背景:左心室射血分数(LVEF)≤35%的患者是心源性猝死(SCD)的高危人群,可从植入式心律转复除颤器(ICD)治疗中获益。急性心肌梗死后的头40天内不需要植入ICD。方法:这是一项在Cottbus心脏中心进行的回顾性研究。对2015年2月至2018年2月26例WCD患者进行回顾性分析和随访。从我们的临床数据库和LifeVest网络中回顾性获得患者人口统计资料、除颤治疗和每日佩戴次数。随访结束时询问患者实际NYHA分级和植入ICD。结果:25例患者(平均年龄65岁,22例男性,3例女性)在心脏手术(21例CABG, 1例AVR, 1例AVR + CABG, 1例AVR + MVR, MVR + CABG)后因心力衰竭(平均EF = 24%)而接受WCD治疗。WCD平均每天使用22.1 (SD±2.7)小时,使用85天(SD±35)。当时检测到11.96 (SD±15)例事件,但未进行治疗,1例进行除颤,未见心脏骤停。随访结束时(12个月,SD±9)对20例患者进行问询。所有患者均存活,其中5例(25%)植入ICD。NYHA I级10例(50%),NYHA II级3例(12%),II-III级3例(12%),III级2例(8%),IV级2例(8%)。结论:A WCD是预防心脏手术后心功能恢复期心源性猝死的有效治疗方法。这种治疗具有很高的患者依从性。
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Analysis of Patients with LifeVest after Cardiac Surgery
Background: Patients with left ventricular ejection fraction (LVEF) ≤ 35% are at a high risk of sudden cardiac death (SCD) and benefit from implantable cardioverter-defibrillator (ICD) therapy. ICD implantation is not indicated during the first 40 days after acute myocardial infarction and Methods: This is a retrospective study conducted in the Heart Center in Cottbus. From 02.2015 through 02.2018 26 WCD patients were retrospectively analyzed and followed-up. Patient demographics, defibrillation treatments, and daily wear times were retrospectively obtained from our clinical database and LifeVest network. The patients were questioned about actual NYHA grade and implanted ICD at the end of follow-up. Results: Twenty-five patients (mean age 65, 22 men, 3 women) were treated with a WCD in response to heart failure (mean EF = 24%) after cardiac surgery (21 CABG, 1 AVR, 1 AVR + CABG, 1 AVR + MVR, MVR + CABG). Average daily use of a WCD was 22.1 (SD ± 2.7) hours which were worn for 85 days (SD ± 35). At that time 11.96 (SD ± 15) events were detected but not treated, 1 defibrillation performed and no asystole seen. At the end of follow-up (12 months, SD ± 9) 20 patients were questioned. All of the patients were alive and 5 (25%) of them were with implanted ICD. 10 (50%) patients were in NYHA grade I, 3 (12%) in NYHA grade II, 3 (12%) between grade II-III, 2 (8%) in grade III and 2 (8%) patients in NYHA grade IV. Conclusions: A WCD is an effective therapy for prevention of sudden cardiac death during the recovery period of heart function after cardiac surgery. This is treatment with high patient compliance.
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