新型纤维心脏瓣膜离病人又近了一步

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摘要

在美国,链球菌性咽喉炎是一种常见且可治疗的儿童疾病,但在不太富裕的国家,感染链球菌的儿童可能会患上风湿热,这种疾病会导致失控的炎症攻击身体组织。风湿热通常会损害心脏瓣膜,导致风湿性心脏病,从而导致严重的健康问题,包括心力衰竭。心脏瓣膜可以通过手术替换,但身体仍在生长的儿童可能需要多次、高度侵入性的手术,用更大的瓣膜替换心脏瓣膜,这将使他们处于危险之中。威斯研究所的凯文·基特·帕克和哈佛大学约翰·保尔森工程与应用科学学院(SEAS)的团队发誓要通过创造一种可植入的心脏瓣膜来解决这个问题,这种瓣膜可以和孩子一起生长,最大限度地减少手术并发症和痛苦。
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New, spun-fiber heart valve is a step closer to patients
Strep throat is a common and treatable childhood disease in the US, but in less wealthy countries, children afflicted with strep can develop rheumatic fever, in which runaway inflammation attacks the body's tissues. Rheumatic fever often damages the valves of the heart, causing rheumatic heart disease that can lead to serious health problems, including heart failure. Heart valves can be surgically replaced, but children whose bodies are still growing may need multiple, highly invasive surgeries to replace their valves with larger ones, putting them at risk. Kevin Kit Parker's team at the Wyss Institute and Harvard's John A. Paulson School of Engineering and Applied Sciences (SEAS) vowed to fix this problem by creating an implantable heart valve that grows with a child, minimizing surgical complications and suffering.
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