卵巢子宫内膜异位症患者盆腔疼痛与血清维生素D水平相关

M. Manero, J. Alcázar, P. Ortega
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摘要

目的:探讨血清维生素D水平与卵巢子宫内膜异位瘤患者盆腔疼痛的相关性。设计:前瞻性研究。单位:大学三级医院。患者:前瞻性分析43例患者的血清维生素D水平(A组、无症状患者或轻度痛经患者;B组,中度痛经,C组,重度痛经和/或慢性盆腔疼痛和/或性交困难)诊断为卵巢囊肿子宫内膜异位症,以评估维生素D血清水平与盆腔疼痛之间是否存在相关性。干预措施:血清维生素D水平测定。主要结局指标:血清维生素D水平和骨盆疼痛。结果:43例患者中,5例因患者不连续而最终被排除。A组患者血清维生素D水平平均值(±SD)分别为26、9±04.17 pg/mL, B组患者血清维生素D水平平均值(±SD)分别为16、2±1.4 pg/mL。结论:卵巢子宫内膜异位症患者疼痛症状与血清维生素d水平相关。
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Pelvic Pain is Correlated with Vitamin D Serum Levels in Ovarian Endometriosis
Objective: To determine whether Vitamin D serum levels are correlated with pelvic pain in patients with ovarian endometriomas. Design: Prospective study. Setting: Tertiary-care university hospital. Patient(s): vitamin D serum levels were prospectively analyzed in 43 patients (group A, asymptomatic patients or patients with mild dysmenorrhea; group B, moderate dysmenorrhea and group C, severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who were diagnosed for cystic ovarian endometriosis to assess whether a correlation exists between Vitamin D serum levels and pelvic pain. Intervention(s): Vitamin D serum levels determination. Main outcome measure(s): Vitamin D serum levels and pelvic pain. Result(s): From 43 patients, five cases were ultimately excluded because patients didn´t continuous). The mean (± SD) vitamin D serum levels in group A were 26,9 ± 04.17 pg/mL in group B were 16,2 ±1,4 pg/mL. and group C 10,4 pg/ml ± 2,4 pg/ml Conclusion(s): Pain symptoms in ovarian endometriosis is correlated with vitamin –D serum levels.
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