过去的对立违抗性障碍与成人注意缺陷/多动障碍的关系

J. Dowson
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引用次数: 1

摘要

目的:虽然DSM-IV注意缺陷/多动障碍(ADHD)与DSM-IV品行障碍(CD)确定的反社会行为共病被认为是一种“独特的亚型”,但基于更普遍的共病对立违抗性障碍(ODD),关于这种亚型的有效性的信息较少。目前的研究调查了过去的ODD与过去和最近的ADHD成人精神病理的关系。方法:94例临床转诊成人(男性73例;21名女性)患有DSM-IV型注意力缺陷多动障碍(ADHD),并对其提供信息者填写问卷。结果:59%的男性既往有ODD(伴有或不伴有CD), 42%的男性既往有CD(伴有或不伴有ODD), 36%的男性既往有ODD和CD;女性分别为57%、33%和29%。在患有DSM-IV ADHD“合并”型(即ADHD最常见的表现)的男性中,过去的ODD评分与过去的CD评分相比,与过去和最近的ADHD相关的多动/冲动以及过去和最近的功能障碍的相关性更强。在女性中,过去的ODD评分与过去的CD评分相比,也显示出与ADHD特征更强的相关性。在男性和女性中,过去的CD评分(而不是ODD)与人格障碍的特征相关。结论:结果表明,ODD(和ODD病史)与基于共病反社会行为的ADHD亚型的有效性研究相关。鉴别有效亚型对于临床病程和治疗反应的研究是重要的。
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Associations of Past Oppositional Defiant Disorder in Adults with Attention- Deficit/Hyperactivity Disorder
Objective: While DSM-IV Attention-deficit/hyperactivity disorder (ADHD) comorbid with antisocial behav- iours identified by DSM-IV conduct disorder (CD) has been claimed as a 'distinct subtype', there is less information about the validity of a subtype based on the more prevalent comorbidity of oppositional defiant disorder (ODD). The pre- sent study investigated the associations of past ODD with past and recent psychopathology in adults with ADHD. Methods: 94 clinic-referred adults (73 male; 21 female) with DSM-IV ADHD, and their informants, completed question- naires. Results: 59% of males had past ODD (with or without past CD), 42% had past CD (with or without past ODD) and 36% had past ODD and past CD; for females, 57%, 33% and 29% respectively. In males with the DSM-IV ADHD 'combined' type (i.e. the most common presentation of ADHD), ratings of past ODD, when compared with those of past CD, were more strongly correlated with past and recent ADHD-related hyperactivity/impulsivity and with past and recent functional impairment. In females, ratings of past ODD, compared with those of past CD, also yielded stronger correlations with fea- tures of ADHD. In males and females, ratings of past CD (but not of ODD) were correlated with features of personality disorders. Conclusions: The results indicated that ODD ( and a history of ODD) is relevant in studies of the validity of ADHD sub- types based on comorbid antisocial behaviour. Identification of valid subtypes is important for studies of clinical course and response to treatment.
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