6个月至30个月间严重急性营养不良儿童神经发育异常的评估

V. Jain, Swati Patel, N. Agarwal, A. Gaur
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引用次数: 2

摘要

目的:应用印度婴儿发育评估量表(DASII)评估严重急性营养不良的发育异常。设计:基于医院的前瞻性分析研究。单位:瓜廖尔Gajra Raja医学院Kamla Raja医院儿科。参与者:2015年3月至2017年1月期间入院的6个月至30个月的世卫组织标准的严重急性营养不良儿童。方法:首先按照WHO的SAM指南对患者进行管理。在稳定期结束时,通过印度婴儿发育评估量表(DASII)进行详细的神经学检查以寻找神经学缺陷。结果:共入组70例。病例的平均发育商数为79.7(23.5),而总体平均值为112.28(10.7)(p 11.5cm[91.5(16.4)])。通过对发育不良患者的分析发现,与未发育不良患者相比,发育不良患者的运动DQ (chi 2 4.1, p值0.023)、精神DQ (chi 2 2.9, p值0.038)和平均DQ (chi 2 3.1, p值0.036)较低的比例显著高于发育不良患者。结论:SAM患者有较低的精神DQ和运动DQ。低MUAC与低运动DQ相关。发育迟缓与低运动和智力DQ有关。
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Assessment of neurodevelopmental abnormalities in children with severe acute malnutrition between the age of 6 months to 30 months
Objectives : To assess the developmental abnormalities in Severe Acute Malnutrition using Developmental Assessment Scale for Indian Infants (DASII). Design: Hospital based Prospective Analytical Study. Setting : Department of Pediatrics, Kamla Raja Hospital, Gajra Raja Medical College, Gwalior. Participants: Children with severe acute malnutrition as per criteria of WHO between the age of 6 months and 30 months admitted in the hospital between March 2015 to January 2017. Method: Patients were first managed as per WHO guidelines of SAM. At the end of stabilization phase detailed neurological examination was done to look for neurological deficits by Development Assessment Scale for Indian Infants (DASII). Results: A total of 70 cases were enrolled. Mean Development Quotient for cases was 79.7(23.5) against a population mean of 112.28(10.7) (p 11.5cm [91.5(16.4)]. On analyzing patients having stunting, it was found that a significant proportion of them had low Motor DQ (chi 2 4.1, p value 0.023), low Mental DQ (chi 2 2.9, p value 0.038), and low Mean DQ (chi 2 3.1, p value 0.036) when compared to patients not having stunting. Conclusions : SAM patients have both low Mental DQ and Motor DQ. Low MUAC is associated with Low Motor DQ. Stunting is associated with low Motor and Mental DQ.
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