帕金森氏病的疾病修饰治疗——最新进展

V. Chandran, D. Grosset
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引用次数: 0

摘要

对帕金森氏病(PD)神经退行性变的病理过程的进一步了解正在导致许多疾病修饰剂的开发。这些包括新药和重新利用的药物。这些疾病修饰疗法中的一些作用于通过基因突变确定的细胞靶点,而另一些作用于我们已知的PD中受影响的其他细胞过程。本综述提供了该领域进展的最新情况,并强调了一些特别感兴趣的领域。
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Disease modifying treatments for Parkinson’s disease – an update
An improved understanding of the pathological processes leading to neurodegeneration in Parkinson’s disease (PD) is leading to the development of a number of disease modifying agents. These include both novel and repurposed drugs. Some of these disease modifying therapies act on cellular targets that have been identified by genetic mutations, while others act on other cellular process which we know are affected in PD. This review provides an update on the progress in the field, and highlights some areas of special interest.
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审稿时长
8 weeks
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