Clinical case of sebaceous gland ectopia in the esophagus — characteristics of endoscopic diagnosis

In most of the previously discussed cases, sebaceous gland ectopia (SGE) was described in tissues derived from the ectoderm. Only a small number of publications reported cases of SGE in the esophagus (endoderm organ). The article presents a clinical case of a 68-year-old male patient without complaints from the gastrointestinal tract, however, there were multiple white overlays in the distal esophagus revealed during esophagogastroduodenoscopy. After the morphological examination, the diagnosis of SGE of the esophagus was established. Currently, there is no data in the world literature on the possible malignant transformation of SGE in the esophagus. In an asymptomatic disease course, this group of patients does not need specific drug therapy and/or endoscopic mucosal resection. If there are symptoms of reflux esophagitis, anti-reflux therapy may be prescribed. The main and, most likely, the only possible method of diagnosing this form of neoplasia is endoscopic, accompanied by the mandatory sampling of biopsy material for morphological examination. Conducting a standard EGDS must necessarily include examination using narrow-band imaging or chromoendoscopy of the esophageal mucosa. KEYWORDS: sebaceous gland ectopia, endoscopy, esophagus, narrow-band imaging, esophagogastroduodenoscopy, chromoendoscopy. FOR CITATION: Lozovaya V.V., Gusarova O.A., Malikhova O.A., Tumanyan A.O. Clinical case of sebaceous gland ectopia in the esophagus — characteristics of endoscopic diagnosis. Russian Medical Inquiry. 2023;7(5):318–322 (in Russ.). DOI: 10.32364/2587-6821-2023-7-5-10.