外耳炎的合理治疗方法

A. V. Gurov, A. V. Muzhichkova
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引用次数: 1

摘要

近年来,有越来越多的电话呼叫耳鼻喉专科有关外耳炎。这些疾病的特点是主要病原体的抗生素耐药性,以及存在明显的疼痛症状。在60-98%的病例中,外耳道炎症是由细菌引起的。铜绿假单胞菌在微生物景观中占据主导地位-平均高达78%,而金黄色葡萄球菌仅在9-27%的病例中播种。尽管外耳炎的治疗方法多种多样,但合理治疗外耳炎仍是耳鼻喉科亟待解决的问题之一。外耳炎的综合治疗是必要的,包括对病因的直接影响,以及疼痛的缓解。在绝大多数情况下,外耳炎的一线经验性治疗应该是外用抗菌药物。以下联合药物成功用于治疗外耳炎:含联合抗生素(氨基糖苷新霉素+环多肽多粘菌素B +表面麻醉剂利多卡因)的滴耳液。早期联合应用抗生素治疗外耳炎是获得快速、可靠临床结果的关键。关键词:外耳炎、细菌性中耳炎、滴耳液、联合抗生素、氨基糖苷、环多肽、表面麻醉剂、新霉素、多粘菌素B、利多卡因。引用本文:Gurov A.V., Muzhichkova A.V.外耳炎的合理治疗方法。俄罗斯医学调查。2022;6(7):404 - 410(俄文)。DOI: 10.32364 / 2587-6821-2022-6-7-404-410。
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Rational approach to the treatment of otitis externa
In recent years, there has been an increased number of calls to ENT specialists concerning otitis externa. These conditions are characterized by antibiotic resistance of key pathogens, as well as the presence of significant pain symptoms. In 60–98% of cases, inflammation in the external auditory canal has a bacterial etiology. Pseudomonas aeruginosa occupies a leading place in the microbial landscape — up to 78% on average, while Staphylococcus aureus is sown only in 9–27% of cases. Rational therapy of otitis externa is one of the urgent problems of otorhinolaryngology, despite the large variety of treatment methods. It is necessary to use complex therapy of external otitis, including a direct effect on the etiological factor, as well as pain relief. In the vast majority of cases, the frontline empirical therapy of otitis externa should be topical antimicrobial agents. The following combined drug is successfully used for the treatment of otitis externa: ear drops containing a combined antibiotic (aminoglycoside neomycin + cyclic polypeptide polymyxin B + topical anesthetic lidocaine). Early therapy of otitis externa with a combined antibiotic is the key to a fast and reliable clinical result. KEYWORDS: otitis externa, bacterial otitis, ear drops, combined antibiotic, aminoglycoside, cyclic polypeptide, topical anesthetics, neomycin, polymyxin B, lidocaine. FOR CITATION: Gurov A.V., Muzhichkova A.V. Rational approach to the treatment of otitis externa. Russian Medical Inquiry. 2022;6(7):404– 410 (in Russ.). DOI: 10.32364/2587-6821-2022-6-7-404-410.
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