Treatment of chromoblastomycosis with calciferol; report of three cases.

This report deals with the results of the treatment of chromoblastomycosis with large doses of calciferol. The use of calciferol in the treatment of this disorder originated with Latapi, * who believes that calciferol dissolves the granulomatous infiltrate of tuberculous diseases and thus enables the body to destroy the organism. Since the histologic changes in chromoblastomycosis are also granulomatous in character, it occurred to me to use calciferol in patients showing the extensive nodules and patches with a hard, verrucous surface typical of the advanced stages of the disease. Previous treatment had failed to benefit these patients. The high incidence of chromoblastomycosis in Costa Rica presents a serious problem. REPORT OF CASES Case1.—A 62-year-old man, a carpenter, was seen in the outpatient department of the hospital on Jan. 7, 1953, with the history of having injured his hand on a piece of wood while at work a year previously. A