内收肌痉挛性发音障碍CO2激光类甲状腺肌神经切除术后发音效果的回顾性分析

R. Bidaye
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摘要

简介:内收肌痉挛性发音障碍(ADSD)是一种局灶性喉张力障碍,其特征是在说话时喉部肌肉痉挛。在甲状腺样肌注射肉毒杆菌毒素仍然是治疗ADSD的金标准。然而,由于肉毒杆菌毒素注射需要定期重复,因此声音质量在较长时间内波动。经口喉镜下CO2激光类甲状腺肌神经切除术(TAM)是治疗ADSD的一种有效方法。它能在更长的时间内持续改善声音。方法:对14例确诊为ADSD的患者(女5例,男9例)进行经口腔显微喉镜CO2激光TAM检查,年龄19 ~ 64岁。数据收集时间为2014年1月至2016年12月的3年多。在手术3个月和12个月结束时,将GRBAS量表以及语音和视频喉频闪(VLS)样本的多维语音程序(MDVP)分析与术前读数进行比较。结果:9例(64.2%)患者术后3个月及12个月评分均有改善。12例(85.7%)患者术后12个月劳损改善。手术3个月后,14例VLS患者中有9例(64.3%)痉挛得到改善,具有统计学意义。结论:这种创新的手术技术对于寻求病情改善的ADSD患者是一种很好的替代治疗方法。
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Retrospective Analysis of Phonatory Outcomes after CO2 Laser Thyroarytenoid Myoneurectomy in Patients with Adductor Spasmodic Dysphonia
Introduction: Adductor spasmodic dysphonia (ADSD) is a focal laryngeal dystonia characterized by spasms of laryngeal muscles during speech. Botulinum toxin injection in the Thyroarytenoid muscle remains the gold-standard treatment for ADSD. However, as Botulinum toxin injections need to be repeated periodically, the voice quality fluctuates over a longer period. A Microlaryngoscopic Transoral approach to CO2 laser Thyroarytenoid myoneurectomy (TAM) has been reported as an effective technique for treatment of ADSD. It provides sustained improvement in the voice over a longer duration. Methods : Trans oral Microlaryngoscopic CO2 laser TAM was performed in 14 patients (5 females and 9 males), aged between 19 and 64 years who were diagnosed with ADSD. Data was collected from over 3 years starting from Jan 2014 – Dec 2016. GRBAS scale along with Multidimensional voice programme (MDVP) analysis of the voice and Video laryngo-stroboscopic (VLS) samples at the end of 3 and 12 months of surgery would be compared with the pre-operative readings. Results: A total of 9 (64.2%) patients showed an improvement in grade after 3 months as well as 12 months after the surgery. While 12 (85.7%) patients showed an improvement in strain after 12 months of surgery. The spasms on VLS showed an improvement in 9 (64.3%) out of 14 cases after 3 months of surgery which was proven to be statistically significant. Conclusion : This innovative surgical technique is a good alternative treatment for ADSD patients who seek a definite improvement of their condition.
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