Evaluation of the serum lipid profile and dietary intake in patients undergoing cholecystectomy

Introduction: New findings suggest that gallbladder not only plays a role in control of concentration and storage of the bile acids, but also, may be effective on nutrients metabolism, in particular on fat metabolism. Objective: This study aimed to determine the effects of cholecystectomy on serum lipid parameters. Materials and methods: This cross-sectional study was conducted on seventy patients who were undergoing cholecystectomy. The serum concentration of lipoproteins, weight, BMI, and dietary intake of subjects were assessed before and one month after the cholecystectomy operation. Results: No significant difference was found regarding serum concentration of triglycerides, total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) to LDL proportion, while, HDL concentration represented a significant reduction after the cholecystectomy. No significant difference was observed in terms of the dietary intake of energy, fat, protein, carbohydrate, fiber, saturated and unsaturated fat before and after the surgery. Conclusion: We showed that cholecystectomy decreases the HDL-C by the day of 30 after surgery, however, other biomarkers such as lipoproteins, weight, and BMI, did not differ significantly.Besides, the stability of the serum levels of lipoproteins preand post-cholecystectomy may be due to the insignificant changes in factors related to diet.