Systemic structural hypothesis of aging

Phenomenon of aging came to existence simultaneously with formation of cell associations and multicellular organisms and played an adaptive role at the early stages of evolution. This phenomenon may be the result of formation of mechanisms that control cellular growth in compliance with nutrient factors limit. Multicellular organisms function as complex systems where the cell division is regulated both by intracellular processes and general systemic organization. The developmental process is determined by a kinetic curve of population growth, which is typical of every cell association. The systemic structural hypothesis considers every multicellular organism as a system that consists of various cellular associations in symbiotic interaction. One of these associations limits the developmental kinetics of the whole organism. Life duration is determined by potential of limiting cell association stem cells. It is offered to introduce a special term – regeneration submodule a unit that consists of cells and tissues which have a general regeneration complex – a group of stem cells that renovate strictly these cells and tissues. Such regeneration submodules are formed within organs and systems; one of them is a dominating unit which determines the life duration.