2019冠状病毒病相关毛霉病伴额骨骨髓炎

N. Gupta, R. Gupta, Rajiv Goel, D. Gautam, V. Singh
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引用次数: 0

摘要

在2019冠状病毒病(COVID-19)大流行期间,报告的COVID-19相关毛霉菌病(CAM)病例不断增加。这可能直接归因于COVID-19感染或相关的未被识别的未控制的高血糖,加上使用类固醇和IL-6抑制剂等COVID-19治疗策略。由于毛霉病是进展最迅速的真菌感染之一,早期诊断和早期适当治疗对于降低死亡率至关重要。鼻-眶-脑和肺毛霉菌病是CAM最常见的表现。毛霉病引起的骨髓炎是非常罕见的,尽管有少数上颌骨受累的病例报道了CAM。我们报告一个非常罕见和具有挑战性的病例,广泛的额骨骨髓炎患者与额窦炎和没有眶或上颌骨受累。
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COVID-19 associated mucormycosis with frontal bone osteomyelitis
During the coronavirus disease 2019 (COVID-19) pandemic, increasing cases of COVID-19 associated mucormycosis (CAM) have been reported. This may be attributed directly to the COVID-19 infection or the associated unrecognised uncontrolled hyperglycaemia compounded by the use of COVID-19 treatment strategies such as steroids and IL-6 inhibitors. As mucormycosis is one of the most rapidly progressing fungal infection, an early diagnosis and early appropriate management are of prime importance in reducing mortality. Rhino-orbital-cerebral and pulmonary mucormycosis have been the most common presentations of CAM. Osteomyelitis in mucormycosis is very rare, although a few cases of maxillary bone involvement have been reported with CAM. We report a very rare and challenging case of extensive frontal bone osteomyelitis in a patient with CAM with frontal sinusitis and without orbital or maxillary bone involvement.
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