一种特殊食物(葡萄糖蜜煎蛋)联合常规治疗对先兆流产的影响:一项随机临床试验

Pub Date : 2022-06-20 DOI:10.15296/ijwhr.2022.25
F. Moradi, M. Tabarrai, S. Hantoushzadeh, M. Sepidarkish, F. Nejatbakhsh, K. Mirzaei, Soodabeh Bioos
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引用次数: 0

摘要

目的:先兆流产是妊娠早期的一种常见疾病,占孕妇的20%。目前,对这种情况没有有效的治疗方法。本研究旨在确定一种特殊食物(葡萄糖蜜煎蛋)结合传统疗法对先兆流产的影响。材料与方法:本随机对照临床试验将93例妊娠16周以内有轻度或中度阴道出血的孕妇分为两组。对照组(n = 47)每日使用黄体酮400 mg栓剂,禁欲、禁欲。干预组(n = 46)食用葡萄糖蜜煎蛋,与对照组一样进行常规治疗。如果怀孕持续到20周,治疗就被认为是成功的。最后比较两组患者流产风险(流产率)和阴道出血持续时间。结果:对照组流产风险为26%(12 / 45),干预组流产风险为15%(7 / 45)。两组间差异无统计学意义(风险比:0.69,95% CI: 0.37 ~ 1.30, P= 0.197)。此外,干预组与对照组的阴道出血持续时间无显著差异(P= 0.699)。结论:食用“葡萄糖蜜煎蛋”与流产风险降低无显著统计学意义。
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The Effects of a Special Food (Fried Eggs With Grape Molasses) on Threatened Miscarriage in Combination With Conventional Therapies: A Randomized Clinical Trial
Objectives: Threatened miscarriage is a common disorder in early pregnancy and is seen in 20% of pregnant women. Currently, there is no effective therapeutic solution for this condition. This study aimed to determine the effects of a special food (fried egg with grape molasses) on threatened miscarriage in combination with conventional therapies. Materials and Methods: This randomized controlled clinical trial was conducted on 93 pregnant women with mild or moderate vaginal bleeding up to 16 weeks of gestation in two groups. The control group (n = 47) used progesterone 400 mg suppository daily with abstinence from sexual intercourse and physical activity. The intervention group (n = 46) consumed fried eggs with grape molasses and the routine treatment like the control group. The treatment was considered successful if the pregnancy continued up to 20 weeks. Finally, the risk of abortion (miscarriage rate) and the duration of vaginal bleeding were compared between two groups. Results: The risk of abortion in the control group was about 26% (12 of 45 pregnancies), while in the intervention group, it was 15% (7 of 45 pregnancies). This result was not statistically significant between the two groups (Risk ratio: 0.69, 95% CI: 0.37-1.30, P= 0.197). Additionally, no significant difference was detected regarding the duration of vaginal bleeding between the intervention and control groups (P= 0.699). Conclusions: There is no significant statistical relationship between the consumption of "fried eggs with grape molasses" and reduction of abortion risk.
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