{"title":"糖尿病和心血管疾病中的炎症:维生素D的新视角","authors":"Lei Su, Haipeng Xiao","doi":"10.1097/XCE.0000000000000062","DOIUrl":null,"url":null,"abstract":"Epidemiological studies indicate an inverse association between vitamin D level and chronic, low-grade systemic inflammatory diseases, such as type 2 diabetes mellitus and cardiovascular disease. Vitamin D signaling may interfere with transcription factors, such as nuclear factor-kappa B, which regulate the expression of inflammatory markers at several levels. In this review, the latest advances in the anti-inflammatory effects of vitamin D from experimental, observational, and small interventional studies will be discussed.","PeriodicalId":72529,"journal":{"name":"Cardiovascular endocrinology","volume":"10 1","pages":"127–131"},"PeriodicalIF":0.0000,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Inflammation in diabetes and cardiovascular disease: a new perspective on vitamin D\",\"authors\":\"Lei Su, Haipeng Xiao\",\"doi\":\"10.1097/XCE.0000000000000062\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Epidemiological studies indicate an inverse association between vitamin D level and chronic, low-grade systemic inflammatory diseases, such as type 2 diabetes mellitus and cardiovascular disease. Vitamin D signaling may interfere with transcription factors, such as nuclear factor-kappa B, which regulate the expression of inflammatory markers at several levels. In this review, the latest advances in the anti-inflammatory effects of vitamin D from experimental, observational, and small interventional studies will be discussed.\",\"PeriodicalId\":72529,\"journal\":{\"name\":\"Cardiovascular endocrinology\",\"volume\":\"10 1\",\"pages\":\"127–131\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cardiovascular endocrinology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/XCE.0000000000000062\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular endocrinology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/XCE.0000000000000062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Inflammation in diabetes and cardiovascular disease: a new perspective on vitamin D
Epidemiological studies indicate an inverse association between vitamin D level and chronic, low-grade systemic inflammatory diseases, such as type 2 diabetes mellitus and cardiovascular disease. Vitamin D signaling may interfere with transcription factors, such as nuclear factor-kappa B, which regulate the expression of inflammatory markers at several levels. In this review, the latest advances in the anti-inflammatory effects of vitamin D from experimental, observational, and small interventional studies will be discussed.
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