{"title":"生殖/发育毒性筛选试验(OECD TG 421)和结合重复剂量毒性研究与生殖/发育毒性筛选试验(OECD TG 422)","authors":"Tg","doi":"10.1787/9789264304741-25-en","DOIUrl":null,"url":null,"abstract":"Weights of: (parents only) testes, epididymides, prostate and seminal vesicles with coagulating glands (OECD TG 421 and TG 422), plus adrenals (OECD TG 422 only). Optional organ weights could include levator ani plus bulbocavernosus muscle complex, Cowper’s glands and glans penis in males, and paired ovaries and uterus (including cervix). Thyroid gland weight could be measured (after fixation) in all adults and PND 13 pups (OECD TG 421 and TG 422).","PeriodicalId":19458,"journal":{"name":"OECD Series on Testing and Assessment","volume":"21 4 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Reproduction/Developmental Toxicity Screening Test (OECD TG 421) and Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (OECD TG 422)\",\"authors\":\"Tg\",\"doi\":\"10.1787/9789264304741-25-en\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Weights of: (parents only) testes, epididymides, prostate and seminal vesicles with coagulating glands (OECD TG 421 and TG 422), plus adrenals (OECD TG 422 only). Optional organ weights could include levator ani plus bulbocavernosus muscle complex, Cowper’s glands and glans penis in males, and paired ovaries and uterus (including cervix). Thyroid gland weight could be measured (after fixation) in all adults and PND 13 pups (OECD TG 421 and TG 422).\",\"PeriodicalId\":19458,\"journal\":{\"name\":\"OECD Series on Testing and Assessment\",\"volume\":\"21 4 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-09-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"OECD Series on Testing and Assessment\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1787/9789264304741-25-en\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"OECD Series on Testing and Assessment","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1787/9789264304741-25-en","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Reproduction/Developmental Toxicity Screening Test (OECD TG 421) and Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (OECD TG 422)
Weights of: (parents only) testes, epididymides, prostate and seminal vesicles with coagulating glands (OECD TG 421 and TG 422), plus adrenals (OECD TG 422 only). Optional organ weights could include levator ani plus bulbocavernosus muscle complex, Cowper’s glands and glans penis in males, and paired ovaries and uterus (including cervix). Thyroid gland weight could be measured (after fixation) in all adults and PND 13 pups (OECD TG 421 and TG 422).
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