应对压力的策略和生活质量与MS患者依从治疗建议的关系

A. Kołtuniuk, J. Chojdak-Łukasiewicz
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摘要

介绍。多发性硬化症(MS)是一种慢性中枢神经系统自身免疫性疾病,常见于20-40岁的年轻人。多发性硬化症的发病率在世界范围内呈上升趋势。症状各不相同,取决于受影响的神经系统的哪一部分。压力在多发性硬化症患者中很常见,它可能是与疾病复发相关的危险因素。应对被定义为试图处理压力事件的行为和认知努力。在长期治疗中,疾病修饰疗法用于降低MS进展和严重程度的风险,并降低致残的风险。坚持治疗对药物的有效性起着至关重要的作用。该研究的目的是评估多发性硬化症患者的应对策略和生活质量之间的相关性,这取决于依从性的程度。材料和方法。该研究在226例多发性硬化症患者中进行。结果表明,23.5%的受访者不遵循推荐的治疗方法。坚持治疗和非坚持治疗的患者对其社会和心理方面的生活质量给予了最高的评价。依从性和非依从性患者最常用的应对策略为:积极应对、计划、积极重构、接纳、寻求情感支持和寻求工具支持。另一方面,药物使用是最不常用的策略,无论依从程度如何。使用应对压力策略,积极解决问题和寻求支持,在MS患者坚持治疗建议的生活质量中起着积极的作用。回避策略的使用,即不采取行动以及自责,降低了MS患者的生活质量,无论是遵循建议还是不遵循建议。(JNNN 2021; 10 (3): 112 - 119)
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Strategies of Coping with Stress and the Quality of Life in Relation to the Adherence to Therapeutic Recommendations in MS — Affected Patients
Introduction. Multiple sclerosis (MS) is a chronic, autoimmune disease of the central nervous system, which affects young adults between 20–40 years old. The incidence of MS is increasing worldwide. The symptoms vary and depend on which part of the nervous system is affected. Stress is very common in patients with MS. It can be a risk factor related with relapses of the disease. Coping is defined as the behavioural and cognitive efforts used in an attempt to deal with stressful events. In a long-term treatment, disease modifying therapies are used to reduce the risk of the progression and severity of MS, and reduce the risk of disability. The adherence to therapy has a crucial role in the effectiveness of drugs.Aim. The aim of the study was to assess the correlation between coping strategies and quality of life in multiple sclerosis patients depending on the degree of adherence.Material and Methods. The study was conducted in 226 patients suffering from MS.Results. It was demonstrated that 23.5% of respondents do not follow recommended treatments. Both adherent and non-adherent patients gave the highest grade to their quality of life in its social and psychological aspects. The most often used strategies of coping with stress both in adherent and non-adherent patients were as follows: active coping, planning, positive reframing, acceptance, seeking emotional support and seeking instrumental support. On the other hand, substance use was the least frequently used strategy, irrespective of the adherence level.Conclusions. The use of the coping-with-stress strategy, associated with an active problem solving and seeking support, plays a positive role in the quality of life of MS patients adhering to therapeutic recommendations. The use of avoidance strategies, i.e. the not taking of actions as well as self-blaming, reduces the quality of life in MS patients, both adherers and non-adherers to recommendations. (JNNN 2021;10(3):112–119)
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