{"title":"基于聚降冰片烯的神经接口微电极阵列","authors":"A. Hess, J. Dunning, D. Tyler, C. Zorman","doi":"10.1109/SENSOR.2007.4300360","DOIUrl":null,"url":null,"abstract":"This paper reports the development of a mechanically-flexible microfabricated flat interface nerve electrode using polynorbornene (PNB) as the structural material. The device consists of two electrode arrays each fabricated on a photolithographically-defined PNB base with thin film Pt electrodes and a photolithographically patterned PNB capping layer. The two arrays are inserted into a silicone housing designed to create a flat interface between the electrodes and the nerve bundle. Electrical tests showed that the resistance of the Pt electrode interconnect traces are unaffected by flexing around a 1.8 mm radius. Electrical testing in phosphate-buffered saline (PBS) shows that resistance of the traces is about 3 kOmega. A 10 day leakage current test in PBS did not produce a detectable change in leakage current. These and other tests indicate that a PNB multilayer system may be viable for microfabricated electrodes.","PeriodicalId":23295,"journal":{"name":"TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference","volume":"28 1","pages":"1235-1238"},"PeriodicalIF":0.0000,"publicationDate":"2007-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":"{\"title\":\"A Polynorbornene-Based Microelectrode Array for Neural Interfacing\",\"authors\":\"A. Hess, J. Dunning, D. Tyler, C. Zorman\",\"doi\":\"10.1109/SENSOR.2007.4300360\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This paper reports the development of a mechanically-flexible microfabricated flat interface nerve electrode using polynorbornene (PNB) as the structural material. The device consists of two electrode arrays each fabricated on a photolithographically-defined PNB base with thin film Pt electrodes and a photolithographically patterned PNB capping layer. The two arrays are inserted into a silicone housing designed to create a flat interface between the electrodes and the nerve bundle. Electrical tests showed that the resistance of the Pt electrode interconnect traces are unaffected by flexing around a 1.8 mm radius. Electrical testing in phosphate-buffered saline (PBS) shows that resistance of the traces is about 3 kOmega. A 10 day leakage current test in PBS did not produce a detectable change in leakage current. These and other tests indicate that a PNB multilayer system may be viable for microfabricated electrodes.\",\"PeriodicalId\":23295,\"journal\":{\"name\":\"TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference\",\"volume\":\"28 1\",\"pages\":\"1235-1238\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/SENSOR.2007.4300360\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/SENSOR.2007.4300360","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Polynorbornene-Based Microelectrode Array for Neural Interfacing
This paper reports the development of a mechanically-flexible microfabricated flat interface nerve electrode using polynorbornene (PNB) as the structural material. The device consists of two electrode arrays each fabricated on a photolithographically-defined PNB base with thin film Pt electrodes and a photolithographically patterned PNB capping layer. The two arrays are inserted into a silicone housing designed to create a flat interface between the electrodes and the nerve bundle. Electrical tests showed that the resistance of the Pt electrode interconnect traces are unaffected by flexing around a 1.8 mm radius. Electrical testing in phosphate-buffered saline (PBS) shows that resistance of the traces is about 3 kOmega. A 10 day leakage current test in PBS did not produce a detectable change in leakage current. These and other tests indicate that a PNB multilayer system may be viable for microfabricated electrodes.