一锅反应制备的两种新型咪唑基Cu(II)骨架的生物活性

Amani Direm, M. Abdelbaky, K. Sayın, A. Cornia, O. Abosede, S. García‐Granda
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引用次数: 0

摘要

通过一锅反应合成了咪唑和柠檬酸两种新型五配位铜(II)配合物。对所得化合物的生物学筛选结果表明,它们具有良好的抗菌和抗真菌活性,是一种有前景的材料。此外,所得到的生物学结果已通过化学反应性计算得到证实。
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Biological activity of two new imidazole-based Cu(II) frameworks resulting from a one-pot reaction
Two new penta-coordinated copper(II) complexes with mixed-ligands, namely: imidazole and citric acid have been synthesized and obtained from a one-pot reaction. The biological screening of the resulting compounds has shown that they could be considered as promising materials with interesting antimicrobial and antifungal inhibition activities. Moreover, the obtained biological results have been confirmed by undertaking chemical reactivity calculations.
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