系统评价:饮食干预只能降低儿童缺铁性贫血的风险

Gihan Ahmad, Mona Abd-Elmotaleb, Hanaa Ahmed, E. Hammad
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摘要

缺铁性贫血是世界范围内与营养不良有关的最常见的贫血类型。这是发展中国家的一个主要问题。目的:确定饮食干预对IDA发生的影响。方法:本系统评价纳入6篇纳入8个合格结局的文献,共纳入676例,无病例339例,对照组337例。饮食干预主要是每天餐前或餐后食用3040g左右的肝脏、羊肝、鸡肝,或12个鸡蛋、或30个红枣等。结果:临床痊愈-临床症状完全消失,血红蛋白恢复正常。临床有效-临床症状缓解,HB升高>15 g/dl。无效-临床症状无改善或明显改善,且HB升高至15 g/dl。饮食干预与临床疗效的平均变化相关,从94.0%到100.0%。6项试验均提高了饮食干预的临床效果,其中3项试验的临床效果有统计学上的提高。异质性检验显示各研究间无显著差异,故采用固定效应模型。饮食干预对IDA患儿的总体汇总估计为5.03 (95%)CI: 3.098.18, Z = 6.50, P<0.001。结论:饮食干预对IDA患儿具有良好的效果。
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Systematic Review: Dietary Intervention only Decreases the Risk of Iron Deficiency Anemia among Children
ron Deficiency Anemia is the most common type of anemia related to malnutrition worldwide. It represents a major problem in developing countries. Purpose: To determine the effect of dietary intervention only on the occurrence of IDA. Methods: In 6 articles with 8 eligible outcomes, a total of 676 individuals were included within the present systematic review with no of cases 339 and 337 control. Dietary intervention is mainly to eat about 3040 g of liver, sheep liver, chicken liver, or 12 eggs, or 30 red dates, etc. before or after the meal once a day. Result: clinical recovery—clinical symptoms disappeared completely, and hemoglobin returned to normal. Clinically effective—clinical symptoms relieved, and the rise of HB >15 g/dl. Invalid— clinical symptoms did not improve or obviously improve, and the rise of HB to 15 g/dl. Dietary intervention was associated with an average change in clinical effectiveness from 94.0% to 100.0%. The clinical effect was increased in dietary intervention in all six trials, among which three trials had a statistical increase of clinical effect. Tests for heterogeneity showed no significant differences across studies, thus the fixed effect model was employed. The overall pooled estimate of or in the dietary intervention on children with IDA was 5.03 (95%) CI: 3.098.18, Z = 6.50, P<0.001. Conclusion: Dietary intervention on children with IDA was established that had a beneficial effect.
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