导论:吡啶

Pyridine Pub Date : 2018-07-18 DOI:10.5772/INTECHOPEN.77969
P. Pandey
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引用次数: 0

摘要

吡啶(C5H5N)是一种芳香化合物,所有的电子都由一个环共享,除了环上每个原子共享的交替双键外,它还形成一个连续的电子环。吡啶是一种独特的类型,环上有氮,通过烷基化和氧化等反应提供叔胺。胺对环上的轻微偶极子负责,因为电子比环上的其他原子更多地被吸引到具有电负性的氮上(氮上的孤对电子)。氢核磁辐射(H- nmr)在分子的邻位、元位和对位上显示出三种不同化学位移的信号。这些化学位移是每个原子的不同电子密度的结果。因此,它不像其他芳香化合物那样稳定(图1)。
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Introductory Chapter: Pyridine
Pyridine (C5H5N), an aromatic compound where all the pi electrons are shared by a ring, forms one continuous circle of electrons besides the alternate double bonds shared by every atom on the circle. Pyridine is a unique type with nitrogen on the ring to provide a tertiary amine by undergoing reactions such as alkylation and oxidation. Amine is responsible for the slight dipole on the ring because electrons are drawn more toward the nitrogen being electronegative (lone pair electrons on the nitrogen) than other atoms in the ring. The H nuclear magnetic radiation (H-NMR) shows three signals at the ortho, meta, and para positions on the molecule in respect of three different chemical shifts. These chemical shifts are the result of the different electron densities for each of these atoms. As a result, this is not stable as other aromatic compounds (Figure 1).
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Introductory Chapter: Pyridine Pyridine: A Useful Ligand in Transition Metal Complexes Diverse Promotive Action of Pyridinecarboxylic Acids on Flowering in Ornamentals and Seedling Growth in Vegetable Crops Role of Pyridines in Medicinal Chemistry and Design of BACE1 Inhibitors Possessing a Pyridine Scaffold Substituent Effect on Pyridine Efficacy as a Chelating Stabilizer
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