孤立性肺纤维性肿瘤患者的多吉-波特综合征:复发性低血糖的罕见病因

Q4 Medicine Journal of Clinical and Translational Endocrinology: Case Reports Pub Date : 2022-06-01 DOI:10.1016/j.jecr.2022.100112

Swaminathan Perinkulam Sathyanarayanan , Raquel Marguerite L. Añel-Tiangco , Noel Dexter L. Tiangco

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引用次数: 0

摘要

doge - potter综合征(DPS)是一种罕见的与孤立纤维性肿瘤相关的副肿瘤，它是间充质梭形细胞肿瘤。DPS的特点是非胰岛素介导的严重低血糖，由于激素原大胰岛素样生长因子(IGF)- 2的释放。在这里，我们提出一个59岁的绅士谁是评估频繁发作的低血糖。进一步检查发现胰岛素、IGF-1和IGF-2水平较低，左侧胸腔内有一个较大的孤立性纤维性肿瘤。切除肿块后，他的低血糖发作完全消失。

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Doege-Potter syndrome in a patient with solitary fibrous tumor of the lung: A rare cause of recurrent hypoglycemia

Doege-Potter syndrome (DPS) is a rare paraneoplastic entity associated with solitary fibrous tumors which are mesenchymal spindle cell neoplasms. DPS is characterized by non-insulin mediated severe hypoglycemia due to release of the prohormone big Insulin like growth factor (IGF)- 2. Here, we present the case of a 59-year-old gentleman who was evaluated for frequent episodes of hypoglycemia. Further work up revealed low insulin, IGF-1 and IGF-2 levels and a large left intrathoracic solitary fibrous tumor. After resection of the mass, his hypoglycemic episodes completely resolved.

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来源期刊

Journal of Clinical and Translational Endocrinology: Case Reports Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

27 weeks

期刊介绍： The journal publishes case reports in a variety of disciplines in endocrinology, including diabetes, metabolic bone disease and osteoporosis, thyroid disease, pituitary and lipid disorders. Journal of Clinical & Translational Endocrinology Case Reports is an open access publication.