卢旺达Butaro卓越癌症中心的血小板输血实践

Irénée Nshimiyimana, Thierry Habyarimana, Callixte Yadufashije, F. Niyonzima
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摘要

背景:为了应对医院对缺乏足够血小板的高需求,2015年,卢旺达国家输血中心采用了单采术来生产更多的血小板。癌症患者中受损骨髓的大量增加被认为是迫切需要输血血小板的主要原因。本研究的目的是描述在Butaro癌症中心的血小板输注实践。方法:对Butaro癌症卓越中心24个月内接受血小板输注的238例患者进行回顾性研究。使用实验室输血登记簿、患者病历文件和门诊开放患者信息软件对研究期间在BCCOE接受血小板输注的所有患者进行识别。使用收集表格记录所有需要的数据。结果:接受血小板输注者中癌症患者209例(87.8%)。这些癌症患者大多患有急性淋巴细胞白血病。在要求的1318个血小板单位中,仅收到925个(70.2%),其中573个(43.4%)为O型恒河猴阳性。在确诊的癌症中,淋巴瘤(χ 2 =7;P= 0.01)与输血后血小板增加率相关,差异有统计学意义。所有诊断出的癌症(卡方=11;P=.03)与输血后血小板增加率相关。结论:不论输注血小板的指征如何,每次输注后血小板计数均有所增加。卫生部必须确保为血小板减少患者提供良好的护理,其中癌症患者最多。
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Platelets Transfusion Practice at Butaro Cancer Centre of Excellence in Rwanda
Background: To respond to the high demand of hospitals for the lack of enough platelets, in 2015, Rwanda national centre for blood transfusion introduced apheresis to produce more platelets. The high increase of impaired bone marrow among cancer patients was declared to be the main cause of the urgent demand of transfused platelets. The aim of this study was to describe the practice of platelets transfusion at Butaro cancer centre. Methodology: A retrospective study of 238 patients who received platelets transfusions at Butaro Cancer Centre of Excellence within a period of 24 months was carried out. Laboratory register books for blood transfusion, patients’ chart files and open clinic patient information software were used to identify all patients who received platelets transfusion at BCCOE during the study period. A collection form was used to record all the required data. Results: A sum of 209 (87.8%) of receivers of platelets transfusion were cancer patients. Majority of those cancer patients had acute lymphoblastic leukaemia. Out of 1318 platelets units requested, only 925(70.2%) were received of which 573(43.4%) were O Rhesus positive. Among diagnosed cancers, Lymphomas (Chi square =7;P=.01) was statistically significant to be associated with the increase rate of platelets after transfusion. The combination of all diagnosed cancers (Chi square=11;P=.03) were associated with the increase rate of platelets after transfusion. Conclusion: Regardless the indication of platelets transfusion, the increase of platelet count was observed after each transfusion. Ministry of health has to ensure the availability of platelets for a good care of thrombocytopenic patients of whom cancer patients are the most.
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