日本尿路感染中分离的耐药细菌可转移耐药性的流行情况

Y. Naide, T. Kawamura, K. Makino, H. Tamura, Tsutomu Watanabe
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引用次数: 7

摘要

许多具有多重耐药的肠杆菌科尿分离株被发现含有传播耐药因子(R因子)。在所调查的每个菌株中,抗性水平几乎是一致的。抗性标记通常作为一个单位转移。即使使用相同的受体菌株,宿主与宿主之间的转移频率也不同。然而,在大肠杆菌K-12亚株之间,R因子的连续转移没有显著差异。讨论了R因子在尿路感染中的作用。
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Prevalence of Transferable Drug Resistance in Drug‐Resistant Bacteria Isolated from Urinary Tract Infections in Japan
Many urinary isolates which belong to the Enterobacteriaceae and bear multiple drug resistance were shown to harbor transmissible resistance factors (R factors). The levels of resistance were almost uniform in every strain investigated. The resistance markers were usually transferred as a unit. Frequency of transfer varied from host to host even when the same recipient strain was employed. However, no remarkable differences were observed in successive transfers of R factors between substrains of Escherichia coli K-12. The role of R factors in urinary tract infection is discussed.
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