胰十二指肠切除术后切除胰腺癌异时性肾转移1例

Y. Igata, Yuta Kobayashi, S. Okubo, J. Shindoh, M. Hashimoto
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引用次数: 0

摘要

多数患者胰腺切除术后复发,预后较差。这是一个初步报告的病人切除孤立肾转移从胰腺癌。该病例为一名58岁男性,因胰腺癌行胰十二指肠切除术。行S1辅助化疗,首次切除9个月后发现左肾小结节10mm。2个月后肾结节增大至15mm,但肿瘤标志物未见增加。肾切除术病理诊断为胰腺源性腺癌。在肾切除术后10个月,吉西他滨治疗未观察到复发的明确证据。当胰腺癌术后新发现肾肿块时,应考虑肾转移作为鉴别诊断。在多学科治疗中,积极手术治疗孤立性肾转移可能有助于提高患者的生存率。
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Resected metachronous renal metastasis of pancreatic cancer after pancreaticoduodenectomy—a case report
: Majority of patients experience recurrence of pancreatic cancer after pancreatectomy which results in poor prognosis. This is an initial report on a patient with resected solitary renal metastasis from pancreatic cancer. The case was a 58-year-old man who underwent pancreaticoduodenectomy for pancreatic cancer. He was on S1 treatment as adjuvant chemotherapy, where 10 mm left renal nodule was detected 9 months after primary resection. The renal nodule increased to 15 mm in 2 months, although there were no increase in tumor markers. Nephrectomy revealed that the pathological diagnosis was adenocarcinoma of pancreatic origin. No definite evidence of recurrence was observed with gemcitabine treatment for 10 months after nephrectomy. When a renal mass is newly detected in the post-operative course of pancreatic cancer, renal metastasis should be considered as a differential diagnosis. Among the multidisciplinary treatments, aggressive surgery for solitary renal metastasis may contribute to better survival in selected patients.
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