2-苯基-3,4-二氢喹唑啉-4-氧基)乙酸金属配合物的合成、表征及其生物应用

M. Hussien, Walid Fathalla, F. Mahmoud, M. Megahed
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引用次数: 0

摘要

研究了2-苯基-3,4-二氢喹唑啉-4-氧基)-乙酸(L1)与Mn 2+、Co 2+、Ni 2+ Cu 2+、Zn 2+离子的配合物,并用元素分析、红外(IR)、1h核磁共振(NMR)、磁矩和热分析等方法对配合物的结构进行了表征。除了对配合物进行理化表征外,还对合成的配合物进行了生物活性检测,以评价其抗菌和抗真菌活性。
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Synthesis and characterization of some metal complexes of 2- Phenyl-3,4-dihydro-quinazolin-4-yloxy)-acetic acid and their Biological Application
2-Phenyl-3,4-dihydro-quinazolin-4-yloxy)-acetic acid (L1) metal complexes with Mn 2+ , Co 2+ , Ni 2+ Cu 2+ , and Zn 2+ ions were studied and the structure of the complexes were elucidated using elemental analyses, infrared (IR), 1 H nuclear magnetic resonance (NMR), magnetic moment and thermal analysis measurements. Besides the characterization of complexes by physicochemical technique, Biological activities of the synthesized complexes were examined against some microbial strains for evaluation of antibacterial and antifungal activities.
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