{"title":"Abrus Precatorius诱导出血性结肠炎","authors":"R. Ganesan, Rajalakshmi Ettiyan","doi":"10.3844/AJPTSP.2015.40.45","DOIUrl":null,"url":null,"abstract":"Abrus Precatorius commonly known as Rosary bead or Kundumani (Arena, 1986) is an irritant poison affecting almost all major systems of the body with more damage to the gastrointestinal system. The mortality rate is 10 to 15% for a lethal dose of just 1-2 crushed seeds. Following is the case report of hemorrhagic colitis due to the ingestion of a toxic dose of ABRUS seeds (Reedman et al., 2008). Sigmoidoscopy was done to document the hemorrhagic colitis. Client was treated as severe colitis with intra venous antibiotics, intravenous steroids; Oral Mesalamine, Intra venous Pantaprazole and IV fluids. Despite consuming a large amount of the toxin, our client survived.","PeriodicalId":7769,"journal":{"name":"American Journal of Pharmacology and Toxicology","volume":"31 1","pages":"40-45"},"PeriodicalIF":0.0000,"publicationDate":"2015-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Abrus Precatorius Induced Hemorrhagic Colitis\",\"authors\":\"R. Ganesan, Rajalakshmi Ettiyan\",\"doi\":\"10.3844/AJPTSP.2015.40.45\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abrus Precatorius commonly known as Rosary bead or Kundumani (Arena, 1986) is an irritant poison affecting almost all major systems of the body with more damage to the gastrointestinal system. The mortality rate is 10 to 15% for a lethal dose of just 1-2 crushed seeds. Following is the case report of hemorrhagic colitis due to the ingestion of a toxic dose of ABRUS seeds (Reedman et al., 2008). Sigmoidoscopy was done to document the hemorrhagic colitis. Client was treated as severe colitis with intra venous antibiotics, intravenous steroids; Oral Mesalamine, Intra venous Pantaprazole and IV fluids. Despite consuming a large amount of the toxin, our client survived.\",\"PeriodicalId\":7769,\"journal\":{\"name\":\"American Journal of Pharmacology and Toxicology\",\"volume\":\"31 1\",\"pages\":\"40-45\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-09-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Pharmacology and Toxicology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3844/AJPTSP.2015.40.45\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Pharmacology and Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3844/AJPTSP.2015.40.45","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
摘要
Abrus Precatorius通常被称为Rosary珠或Kundumani (Arena, 1986)是一种刺激性毒药,几乎影响身体的所有主要系统,对胃肠道系统的损害更大。1-2粒碾碎的种子致死剂量,死亡率为10% - 15%。以下是因摄入有毒剂量的ABRUS种子而导致出血性结肠炎的病例报告(Reedman et al., 2008)。乙状结肠镜检查记录出血性结肠炎。病人被诊断为严重结肠炎,静脉注射抗生素、类固醇;口服美沙拉明,静脉注射泮他拉唑和静脉输液。尽管摄入了大量毒素,我们的委托人还是活了下来。
Abrus Precatorius commonly known as Rosary bead or Kundumani (Arena, 1986) is an irritant poison affecting almost all major systems of the body with more damage to the gastrointestinal system. The mortality rate is 10 to 15% for a lethal dose of just 1-2 crushed seeds. Following is the case report of hemorrhagic colitis due to the ingestion of a toxic dose of ABRUS seeds (Reedman et al., 2008). Sigmoidoscopy was done to document the hemorrhagic colitis. Client was treated as severe colitis with intra venous antibiotics, intravenous steroids; Oral Mesalamine, Intra venous Pantaprazole and IV fluids. Despite consuming a large amount of the toxin, our client survived.