Ca2+储存与海马突触可塑性

Bruno G. Frenguelli , Andrew J. Irving , Graham L. Collingridge
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引用次数: 22

摘要

多年来,内钙储存(ICSs)在兴奋-收缩耦合和内分泌功能中的重要性已得到充分认识。随着中枢神经系统中ICSs的发现,越来越多的证据表明它们在神经元功能,特别是突触可塑性中的作用。在这篇综述中,我们将重点讨论ICSs在海马突触可塑性中的作用。
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Ca2+stores and hippocampal synaptic plasticity

For many years the importance of internal calcium stores (ICSs) in excitation–contraction coupling and endocrine function has been well recognized. With the discovery of ICSs in the CNS, evidence has accumulated regarding their role in neuronal function, and in particular, synaptic plasticity. In this review we focus on the involvement of ICSs in synaptic plasticity in the hippocampus.

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