微生物代谢产物乳酸存在下种植用Ti6Al4V合金在Hank生物溶液中的耐蚀性评价

L. Benea, N. Simionescu, Dunărea de Jos
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引用次数: 1

摘要

Ti6Al4V等钛合金是生物医学用途中最常用的植入物。选择用于人体特定应用的生物材料的条件是,它应符合物理、化学和生物学特性,更准确地说,它应具有生物相容性、生物功能和最终不可灭菌性。Ti6Al4V合金具有适合许多生物医学应用的机械性能,并且具有优异的耐腐蚀性,这取决于其表面形成稳定的被动氧化膜的存在。我们的研究旨在评价Ti6Al4V在暴露于生物溶液Hank后0 h(浸泡时间)、48 h(浸泡时间)和168 h(浸泡时间)分别添加5 g/L和10 g/L乳酸的耐蚀性与时间的关系。采用电化学方法从断路电位和极化电阻(Rp)两方面评价了Ti6Al4V在添加两种浓度乳酸的Hank生物溶液中的耐蚀性。乳酸之所以被用于这项研究,是因为它是人体血液中少量存在的一种成分,是心肌、大脑和神经系统直接使用的代谢过程所必需的。肌肉中乳酸含量的增加表现为负重运动。这就是为什么了解大量乳酸的存在如何影响植入物是很重要的。该研究还强调了在测试生物医学材料时使用更长的测试时间和更现实的解决方案的重要性。
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Evaluation of Corrosion Resistance of Implant-use Ti6Al4V Alloy in Hank Biological Solution in the Presence of Microorganism's Metabolic Product Lactic Acid
Titanium alloys such as Ti6Al4V is the most used alloy used as implant for biomedical purposes. The conditions for a biomaterial to be selected for a particular application in the human body is that this should to conforms to the physical, chemical and biological characteristics, more precisely to be biocompatible, biofunctional and not ultimately sterilizable. Ti6Al4V alloy has mechanical properties suitable for many biomedical applications and has excellent corrosion resistance, which depends on the presence of a stable passive oxide film forming on its surface. Our study aims to evaluate the corrosion resistance of Ti6Al4V as a function in time with addition of 5 g/L and 10 g/L Lactic acid in biological solution Hank after exposure at 0 h (at immersion time), after 48 h (from immersion) and 168 h (from immersion). The evaluation of corrosion resistance of Ti6Al4V in Hank biological solution with addition of two concentration of Lactic acid it was done by electrochemical methods in terms of open circuit potential and polarization resistance (Rp). Lactic acid is used in this study because it is a component present in human blood in small quantities and is necessary for the metabolic processes used directly by the heart muscle, brain and nervous system. The increased lactic acid content in muscle appears as weight-bearing exercises. This is why it is important to know how the presence of lactic acid in larger quantities affects the implants. The study also highlights the importance of using longer testing times and more realistic solutions when testing biomedical materials.
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