免疫系统作为癌症治疗的关键:用微生物制剂触发其活性

Marina Resendes de Sousa António, Dirk Schulze-Makuch
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引用次数: 4

摘要

化疗和放射治疗等传统方法在治疗癌症方面收效甚微。部分原因与我们对癌症的误解有关:癌症不是起因,而是生命系统衰弱的结果。由毒素、诱变剂或辐射引起的局部细胞压力,加上系统反应减弱或无法支持或保护受到攻击的细胞,导致这些细胞恢复到古老的单细胞生存模式,从而切断与总体有机体的联系,并像个体实体一样保护自己免受威胁。我们假设,加强机体,特别是免疫系统,是比试图消灭癌细胞更有希望治愈癌症的方法。这一假设可以通过旨在通过传统方法(例如,摄入已知可增加免疫系统活性的天然物质,如水果、蔬菜和坚果)、减少癌细胞释放的免疫系统抑制剂(如TGF-β)、通过注射热杀死或基因改变的致病菌,引发免疫系统对受感染区域的大规模反应(发热反应),并将这些结果与传统方法进行比较。
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The immune system as key to cancer treatment: Triggering its activity with microbial agents

Traditional methods such as chemotherapy and radiation therapy offer only limited success in treating cancer. Part of the reason is related to our misunderstanding of what cancer is: it is not the cause but the consequence of a weakened living system. Localized cellular stress, caused by toxins, mutagens or radiation, coupled with a weakened systemic response or inability to support or defend the cells that are under attack, cause these cells to revert to an ancient, unicellular mode of survival, therefore cutting links with the overarching organism and defend themselves from the threat as if they were individual entities. We hypothesize that strengthening the organism, specifically the immune system, is a more promising approach toward a cure for cancer than attempting to exterminate cancer cells. The hypothesis can be tested by experiments that are designed to strengthen the immune system by both traditional means (e.g., ingestion of natural substances known to increase the activity of the immune system, such as fruits, vegetables, and nuts), diminish immune system inhibitors released by cancer cells (e.g., TGF-β), and by the injection of heat-killed or genetically altered pathogenic bacteria to trigger a massive response (fever response) of the immune system into the affected area and compare those results to traditionally used methods.

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