Differences of the changes in tear film with four types of artificial tear treatment on dry eye after phacoemulsification

Objective To study the difference of the tear film changes of four types artificial tear in treatment of dry eye after phacoemulsification by spectral-domain OCT (SD-OCT). Methods This clinical study included 40 patients (40 eyes) having dry eye after phacoemulsification, 10 patients used Tears Naturale Forte Eye Drops (group A), 10 patients used Polyethylene Glycol Eye Drops (group B), 10 patients used Sodium Hyaluronate Eye Drops (group C), 10 patients used Carboxxymethylcellulose Sodium Eye Drop (group D). Total tear meniscus area (TTMA) was measured before and at differeat times after treatment. Results In the group A and B, TTMA was statistically significantly (P <0.05) better than preoperatively at 0 minute, 10 minute, 20 minute, 30 min-ute and 45 minute. In the group C and D, TTMA was statistically significantly (P <0.05) better than preoperatively at 0 minute and 10 minute. Comparison among groups, at 10 minute, TTMA of group B was statistically significantly (P=0.020, P=0.011) better than group C and group D. At 20 minute TT-MA of group A and group B was statistically significantly (P=0.006, P=0.005, P=0.004, P=0.003) better than group C and group D. Even at 45minute, TTMA of group B was statistically significantly (P=0.040, P=0.016) better than group C and group D. Conclusions Polyethylene Glycol Eye Drops and Tears Naturale Forte Eye Drops are better in treatment of dry eye after phacoemulsification, and q1h is recommended. Key words: Artificial tear; Cataract; Tear meniscus; OCT