0.25%布比卡因与0.25%罗哌卡因在小儿下腹部手术患者尾侧麻醉中的比较

Darshana Kumbhre, R. Jain
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摘要

目的和目的:本研究比较0.25%布比卡因和0.25%罗哌卡因在儿童下腹部手术尾侧阻滞中的起效时间、感觉和运动阻断的作用时间以及术后疼痛缓解。方法:采用双盲方法,将50例(2-8岁)ASA I级和II级患者随机分为两组,经尾侧硬膜外注射0.75ml/ kg 0.25%布比卡因(I组)或0.25%罗哌卡因(II组)。所有患者在七氟醚加氧诱导麻醉后均行尾侧阻滞。将所有结果制成表格并进行统计分析。所有统计分析的显著性水平为p0.05)。运动阻滞时间I组为142.227.77 min, II组为120.623.51 min (p < 0.05)。两组患者的平均疼痛评分具有可比性。结论:布比卡因和罗哌卡因的术后疼痛缓解时间几乎相同,但与布比卡因相比,罗哌卡因的运动阻断作用更小,使其成为日托手术的合适药物,特别是在低龄儿童中,安全裕度更高。
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A comparison between 0.25% bupivacaine and 0.25% ropivacaine in caudal anaesthesia in paediatric patients undergoing lower abdominal surgeries
Aims and Objectives: The present study was undertaken to compare the onset time, duration of action of sensory and motor blockade and postoperative pain relief between 0.25% bupivacaine and 0.25% ropivacaine in caudal block for children undergoing lower abdominal surgeries. Method: In a double blind study, 50 patients of (age 2-8 years) ASA grade I and II were randomly allocated in two equal groups to received 0.75ml/ kg of either 0.25% bupivacaine (Group I) or 0.25% ropivacaine (Group II) via caudal epidural route. Caudal block was performed in all patients after induction of anesthesia with sevoflurane and oxygen. All the results were tabulated and analyzed statistically. For all statistical analysis, the level of significance was P 0.05). The duration of motor block in group I was 142.227.77 minutes while in group II it was 120.623.51 minutes (p 0.05). The mean pain score of patients in both groups were comparable. Conclusion: Bupivacaine and Ropivacaine provides almost similar duration of pain relief postoperatively but ropivacaine provides less motor blockade as compared to bupivacaine, making it a suitable agent for day care surgery with increase safety margin particularly in younger children.
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