微生物抗微生物药物耐药性(AMR)的机制

Soamyaa Srivastava
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引用次数: 1

摘要

当人体的自然防御系统无法对抗病原体时,抗生素就出现了。然而,在过去的几十年里,抗生素的过度使用导致了耐药菌株的发展,这对人类来说可能是致命的,因为它们不容易治疗。抗生素的误用和一些不适当的使用导致细菌细胞发生基因突变以适应抗生素环境。人们开发了几种机制,使这种生物体茁壮成长,并对常规治疗过程产生抗药性。综述了细菌对抗生素耐药的可能机制以及在世界范围内克服这一问题的措施。
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An Outrage: The Mechanism of Antimicrobial Resistance (AMR) in Microorganisms
Antibiotics come into the picture when the natural defense system of the body fails to fight against the pathogen. However, the over usage of antibiotics in the last few decades has led to the development of resistant strains that may be fatal to the human race as they are not easily treatable. The misuse and several inappropriate usages have caused genetic mutations in bacterial cells to adapt to the antibiotic environment. Several mechanisms are developed for the organism to thrive and be resistant to conventional treatment processes. The review discusses the possible mechanisms of bacterial resistance to antibiotics and measures to overcome this problem worldwide.
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