用有限解析公式构建特定患者主动脉的复杂三维结构

A. Medvedev
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引用次数: 0

摘要

我们已经开发了一种构造形态学上真实的人类主动脉的几何结构的方法,包括主动脉根(Valsalva窦),胸主动脉,主动脉弓分支,腹主动脉分支血管。在计划手术干预时,在对主动脉血流进行数值模拟时,建立人体主动脉的三维模型是必要的。不同患者的主动脉解剖结构不同,特别是存在各种病理(动脉瘤、狭窄、主动脉夹层)时。基于MRI、CT图像创建个人主动脉模型需要高度精通计算机的专家耗时的手工工作。提出了一种建立人体主动脉三维模型的简单方法。首先,创建一个患者的主动脉(或主动脉的选定部分)的3D模型。为此,在主动脉原始模型的基础上,构建主动脉的三维分析模型。为了构建这样的分析主动脉,有必要将主动脉划分为特征切片,并为每个切片指定定义参数。为了建立另一个患者的主动脉模型,需要根据患者主动脉结构的个体特征取一个基础模型并进行调整。在那里,必要时添加病理区域(狭窄和动脉瘤)。与从头开始创建一个特定患者的主动脉模型相比,修改基本模型所需的时间和精力要少得多。该技术的主要特点之一是易于使用,消除了建立单个患者主动脉的单调体力劳动。由此产生的主动脉三维模型完全可以在3D打印机上进行3D建模和打印。主动脉的各部分以二级平滑度对接(构建的主动脉各部分之间的连续二阶导数)。
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Construction of Complex Three-Dimensional Structures of the Aorta of a Particular Patient Using Finite Analytical Formulas
We have developed a method for constructing the geometry of a morphologically realistic human aorta, including the aortic root (Valsalva sinus), thoracic aorta, aortic arch with branches, abdominal aorta with bifurcation vessels. The creation of a three-dimensional model of the human aorta is necessary when planning surgical interventions, when performing numerical modeling of blood flow in the aorta. The anatomical structure of the aorta differs in different patients, especially in the presence of various pathologies (aneurysms, stenoses, aortic dissection). Creation of an individual human aorta model based on MRI, CT images requires time-consuming manual work of a highly computer skilled specialist. Presented is a simple method of building a 3D model of the human aorta. Initially, a 3D model of the aorta (or selected section of the aorta) of one patient is created. For this purpose, an analytical 3D model of this aorta is constructed from the raw model of the aorta. To build such an analytical aorta, it is necessary to divide the aorta into characteristic sections and specify defining parameters for each section. To build a model of another patient's aorta, a base model is taken and adjusted based on the individual features of the patient's aorta structure. At that, areas of pathology (stenoses and aneurysms) are added if necessary. Correction of the basic model requires much less time and effort than creating an aortic model of a particular patient from scratch. One of the key features of the technique is ease of use, eliminating the monotonous manual labor of building an individual patient's aorta. The resulting three-dimensional model of the aorta is fully ready for 3D modeling and printing on a 3D printer. Sections of the aorta are docked with the second order of smoothness (continuous second derivative between sections of the constructed aorta).
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来源期刊
Mathematical Biology and Bioinformatics
Mathematical Biology and Bioinformatics Mathematics-Applied Mathematics
CiteScore
1.10
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发文量
13
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