{"title":"肉颜色的代谢组学:实际意义","authors":"M. Denzer, F. Kiyimba, G. Mafi, R. Ramanathan","doi":"10.2174/1570164619666211230153145","DOIUrl":null,"url":null,"abstract":"\n\nMeat is biochemically active, and the various pre-and post-harvest processes\ncan affect meat quality. Metabolomics is a valuable tool to elucidate metabolite changes in meat.\nThe overall goal of this study was to provide an overview of various techniques, data analysis, and\napplication of metabolomics in meat color research.\n\n\n\nBoth targeted and non-targeted approaches have been used to determine metabolite profiles in meat. Researchers use gas-, liquid-chromatography, and nuclear magnetic resonance platforms to separate molecules. Metabolomics is used to characterize muscle-specific differences in\ncolor stability, meat tenderness, the impact of aging on meat color, and to determine metabolite profile differences between normal-pH and dark-cutting beef. Color stable muscles have more glycolytic metabolites than color labile muscles.\n\n\n\nThe use of metabolomics has greatly enhanced our understanding of metabolites' role\nin meat quality. There are challenges in data analysis; thus, there is a need for multiple platforms in\norder to obtain comprehensive metabolite libraries specific to food. Metabolomics in combination\nwith wet-laboratory techniques can provide novel insights on the relationship between postmortem\nmetabolism and meat color.\n","PeriodicalId":50601,"journal":{"name":"Current Proteomics","volume":"61 1","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metabolomics of meat color: Practical implications\",\"authors\":\"M. Denzer, F. Kiyimba, G. Mafi, R. Ramanathan\",\"doi\":\"10.2174/1570164619666211230153145\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nMeat is biochemically active, and the various pre-and post-harvest processes\\ncan affect meat quality. Metabolomics is a valuable tool to elucidate metabolite changes in meat.\\nThe overall goal of this study was to provide an overview of various techniques, data analysis, and\\napplication of metabolomics in meat color research.\\n\\n\\n\\nBoth targeted and non-targeted approaches have been used to determine metabolite profiles in meat. Researchers use gas-, liquid-chromatography, and nuclear magnetic resonance platforms to separate molecules. Metabolomics is used to characterize muscle-specific differences in\\ncolor stability, meat tenderness, the impact of aging on meat color, and to determine metabolite profile differences between normal-pH and dark-cutting beef. Color stable muscles have more glycolytic metabolites than color labile muscles.\\n\\n\\n\\nThe use of metabolomics has greatly enhanced our understanding of metabolites' role\\nin meat quality. There are challenges in data analysis; thus, there is a need for multiple platforms in\\norder to obtain comprehensive metabolite libraries specific to food. Metabolomics in combination\\nwith wet-laboratory techniques can provide novel insights on the relationship between postmortem\\nmetabolism and meat color.\\n\",\"PeriodicalId\":50601,\"journal\":{\"name\":\"Current Proteomics\",\"volume\":\"61 1\",\"pages\":\"\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2021-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Proteomics\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.2174/1570164619666211230153145\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Proteomics","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.2174/1570164619666211230153145","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Metabolomics of meat color: Practical implications
Meat is biochemically active, and the various pre-and post-harvest processes
can affect meat quality. Metabolomics is a valuable tool to elucidate metabolite changes in meat.
The overall goal of this study was to provide an overview of various techniques, data analysis, and
application of metabolomics in meat color research.
Both targeted and non-targeted approaches have been used to determine metabolite profiles in meat. Researchers use gas-, liquid-chromatography, and nuclear magnetic resonance platforms to separate molecules. Metabolomics is used to characterize muscle-specific differences in
color stability, meat tenderness, the impact of aging on meat color, and to determine metabolite profile differences between normal-pH and dark-cutting beef. Color stable muscles have more glycolytic metabolites than color labile muscles.
The use of metabolomics has greatly enhanced our understanding of metabolites' role
in meat quality. There are challenges in data analysis; thus, there is a need for multiple platforms in
order to obtain comprehensive metabolite libraries specific to food. Metabolomics in combination
with wet-laboratory techniques can provide novel insights on the relationship between postmortem
metabolism and meat color.
Current ProteomicsBIOCHEMICAL RESEARCH METHODS-BIOCHEMISTRY & MOLECULAR BIOLOGY
CiteScore
1.60
自引率
0.00%
发文量
25
审稿时长
>0 weeks
期刊介绍:
Research in the emerging field of proteomics is growing at an extremely rapid rate. The principal aim of Current Proteomics is to publish well-timed in-depth/mini review articles in this fast-expanding area on topics relevant and significant to the development of proteomics. Current Proteomics is an essential journal for everyone involved in proteomics and related fields in both academia and industry.
Current Proteomics publishes in-depth/mini review articles in all aspects of the fast-expanding field of proteomics. All areas of proteomics are covered together with the methodology, software, databases, technological advances and applications of proteomics, including functional proteomics. Diverse technologies covered include but are not limited to:
Protein separation and characterization techniques
2-D gel electrophoresis and image analysis
Techniques for protein expression profiling including mass spectrometry-based methods and algorithms for correlative database searching
Determination of co-translational and post- translational modification of proteins
Protein/peptide microarrays
Biomolecular interaction analysis
Analysis of protein complexes
Yeast two-hybrid projects
Protein-protein interaction (protein interactome) pathways and cell signaling networks
Systems biology
Proteome informatics (bioinformatics)
Knowledge integration and management tools
High-throughput protein structural studies (using mass spectrometry, nuclear magnetic resonance and X-ray crystallography)
High-throughput computational methods for protein 3-D structure as well as function determination
Robotics, nanotechnology, and microfluidics.