S. Martínez-Bellver, A. Cervera-Ferri, Aina Luque‐García, J. Martínez-Ricós, A. Valverde-Navarro, M. Bataller, Juan Guerrero, V. Teruel-Martí
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Causal relationships between neurons of the nucleus incertus and the hippocampal theta activity in the rat
The nucleus incertus is a key node of the brainstem circuitry involved in hippocampal theta rhythmicity. Synchronisation exists between the nucleus incertus and hippocampal activities during theta periods. By the Granger causality analysis, we demonstrated a directional information flow between theta rhythmical neurons in the nucleus incertus and the hippocampus in theta‐on states. The electrical stimulation of the nucleus incertus is also able to evoke a phase reset of the hippocampal theta wave. Our data suggest that the nucleus incertus is a key node of theta generation and the modulation network.
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