阻塞性睡眠呼吸暂停对腺样体切除术后难治性鼻症状发展的影响

Aneesh A. Patel, C. Brook, Jessica R. Levi
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摘要

目的:慢性鼻炎可能导致手术治疗阻塞性睡眠呼吸暂停(OSA)患者的生活质量持续下降。本研究旨在探讨OSA在小儿腺样体切除术后难治性慢性鼻炎患者中的作用。方法:我们回顾了2012年10月至2018年12月在某学术医疗中心接受腺样体切除术的<18岁有OSA病史的患者的图表,并在诊所进行随访。他们通过现行程序术语(CPT)代码42830和42831进行识别,排除了扁桃体切除术和腺样体切除术的CPT 42820。先前诊断为OSA且有难治性症状的患者与症状缓解的患者使用卡方分析和t检验进行比较。结果:腺样体切除术后出现难治性症状的患者36例(35.0%),无难治性症状的患者52例(37.4%)术前有OSA病史(p=0.80)。在有难治性症状的患者中,平均年龄(3.8岁)和男性(n=24, 66.7%)与无难治性症状的患者中平均年龄(4.42岁)和男性(n=36, 69.2%)所占比例无显著差异。平均呼吸暂停/呼吸不足指数(AHI) (p=0.91)、睡眠研究完成程度(p=0.41)、打鼾史(p=0.92)和扁桃体大小(p=0.42)在两组间无显著差异。然而,有难治性症状的患者的平均体重指数(BMI)(19.58)明显高于无症状的患者(17.77,p=0.04),并且完成的过敏评估次数更高(p=0.02)。结论:虽然腺样体切除术后出现难治性鼻症状的患者的OSA病史和严重程度没有显著差异,但这些患者的BMI和完成过敏评估的程度明显更高。
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The Impact of Obstructive Sleep Apnea on the Development of Refractory Nasal Symptoms After Adenoidectomy
Objectives: Chronic rhinitis may contribute to a persistently decreased quality of life in patients undergoing surgical treatment for obstructive sleep apnea (OSA). This study aimed to characterize the role of OSA in pediatric patients with refractory chronic rhinitis after adenoidectomy.Methods: We reviewed the charts of patients <18 years of age with a history of OSA who underwent adenoidectomy at an academic medical center from October 2012 to December 2018 and that were seen in the clinic for follow-up. They were identified through the Current Procedural Terminology (CPT) codes 42830 and 42831 with the exclusion of CPT 42820 for tonsillectomy and adenoidectomy. Patients with a prior diagnosis of OSA who had refractory symptoms were compared with those who had symptoms resolution using chi-square analysis and t-tests.Results: Thirty-six (35.0%) patients with refractory symptoms following adenoidectomy and 52 (37.4%) patients without refractory symptoms had a history of OSA before surgery (p=0.80). In patients with refractory symptoms, the average age (3.8 years) and male sex (n=24, 66.7%) did not differ significantly from the age (4.42 years) and male sex (n=36, 69.2%) percentages of patients without refractory symptoms. The mean apnea/hypopnea-index (AHI) (p=0.91), completion of the sleep study (p=0.41), history of snoring (p=0.92), and tonsil size (p=0.42) did not differ significantly between the groups. However, patients with refractory symptoms had a significantly higher mean body mass index (BMI) (19.58) than those who did not (17.77, p=0.04) and completed a higher number of allergy evaluations (p=0.02).Conclusions: While the history and severity of OSA did not differ significantly in patients with refractory nasal symptoms after adenoidectomy, these patients had a significantly higher BMI and completion of allergy evaluation.
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